Hyaluronic acid gel characterization using classical rheology and passive microrheology technique

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F14%3APU110555" target="_blank" >RIV/00216305:26310/14:PU110555 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Hyaluronic acid gel characterization using classical rheology and passive microrheology technique

Popis výsledku v původním jazyce

Passive microrheology is a novel approach determining viscoelastic properties of soft materials based on the Brownian motion of inserted probes. From the particle movement one can calculate viscosity in case of Newtonian fluids and viscoelastic parameters (elastic and storage modulus) in case of non-Newtonian fluids. In our work microrheology was utilized to investigate hyaluronic acid gels formed mixing hyaluronic acid solution with cetyltrimethylammonium bromide (CTAB). Four gels of different concentrations of hyaluronic acid and CTAB were prepared. Their microstructure was characterized via video based particle tracking microrheology using three sizes of inserted particles ? 0.1, 0.5, and 1 um to study it s microstructure. All data were compared toclassical rheology results providing informations about the sample macrostructure. Each particle size shows different results corresponding to local microenvironment of the particle in response to the mesh size of the polymer structure an

Název v anglickém jazyce

Hyaluronic acid gel characterization using classical rheology and passive microrheology technique

Popis výsledku anglicky

Passive microrheology is a novel approach determining viscoelastic properties of soft materials based on the Brownian motion of inserted probes. From the particle movement one can calculate viscosity in case of Newtonian fluids and viscoelastic parameters (elastic and storage modulus) in case of non-Newtonian fluids. In our work microrheology was utilized to investigate hyaluronic acid gels formed mixing hyaluronic acid solution with cetyltrimethylammonium bromide (CTAB). Four gels of different concentrations of hyaluronic acid and CTAB were prepared. Their microstructure was characterized via video based particle tracking microrheology using three sizes of inserted particles ? 0.1, 0.5, and 1 um to study it s microstructure. All data were compared toclassical rheology results providing informations about the sample macrostructure. Each particle size shows different results corresponding to local microenvironment of the particle in response to the mesh size of the polymer structure an

Druh

O - Ostatní výsledky

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

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Projekt

<a href="/cs/project/LO1211" target="_blank" >LO1211: Centrum materiálového výzkumu na FCH VUT v Brně - udržitelnost a rozvoj</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů