Preparation and Characterization of Liposomes as Cosmetic Delivery Systems

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F17%3APU124155" target="_blank" >RIV/00216305:26310/17:PU124155 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Preparation and Characterization of Liposomes as Cosmetic Delivery Systems

Popis výsledku v původním jazyce

Besides finding some new sources, cosmetic producers tend to adopt well-known and popular ingredients already used in the health and food sectors. Presented work is focused on characterization of some complex natural sources of phenolics and their encapsulation into liposome nanoparticles. Total phenolics, flavonoids and antioxidant activity of plant extracts was determined spectrophotometrically. Extracts were then packed into liposome particles. Size of prepared liposomes was evaluated by dynamic light scattering and their stability was determined using zeta potential. Encapsulation efficiency of active compounds was evaluated by spectrophotometrical methods. Liposome particles with antioxidant properties were tested for possible genotoxic effects as well as pure extracts. In this work it was found that selected natural sources of phenolics could be packed into liposome particles with high encapsulation efficiency. Neither prepared particles nor pure extracts show genotoxic effect on model organi

Název v anglickém jazyce

Preparation and Characterization of Liposomes as Cosmetic Delivery Systems

Popis výsledku anglicky

Besides finding some new sources, cosmetic producers tend to adopt well-known and popular ingredients already used in the health and food sectors. Presented work is focused on characterization of some complex natural sources of phenolics and their encapsulation into liposome nanoparticles. Total phenolics, flavonoids and antioxidant activity of plant extracts was determined spectrophotometrically. Extracts were then packed into liposome particles. Size of prepared liposomes was evaluated by dynamic light scattering and their stability was determined using zeta potential. Encapsulation efficiency of active compounds was evaluated by spectrophotometrical methods. Liposome particles with antioxidant properties were tested for possible genotoxic effects as well as pure extracts. In this work it was found that selected natural sources of phenolics could be packed into liposome particles with high encapsulation efficiency. Neither prepared particles nor pure extracts show genotoxic effect on model organi

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

<a href="/cs/project/LO1211" target="_blank" >LO1211: Centrum materiálového výzkumu na FCH VUT v Brně - udržitelnost a rozvoj</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů