Rheological properties of hydrogels based on biopolymer and oppositely charged surfactant

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F17%3APU126032" target="_blank" >RIV/00216305:26310/17:PU126032 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Rheological properties of hydrogels based on biopolymer and oppositely charged surfactant

Popis výsledku v původním jazyce

This study is focused on the properties and behaviour of phase-separated hydrogels prepared by interaction of hyaluronan (Hya) with oppositely charged surfactants. Three representatives of surfactants, namely cetyltrimethylammonium bromide, chloride and p-toluensulfonate (CTAB, CTAC, CTAT), were selected for comparison. The method of rheology was used as a crucial one in this research. The fact that the system of Hya-CTAT forms the most rigid hydrogels has been proved. Higher molecular weight of polymer has also direct influence on the volume and stiffness of the hydrogels. The methods of preparation were compared as well. Mixing the stock solutions of entry components appeard to be the most suitable. The final results indicate that studied gels are to a certain extent competitive. Incorporation of hyaluronan into their structure is desirable with respect to its biological activity. This offers a potential usage of these substances in the field of medical applications.

Název v anglickém jazyce

Rheological properties of hydrogels based on biopolymer and oppositely charged surfactant

Popis výsledku anglicky

This study is focused on the properties and behaviour of phase-separated hydrogels prepared by interaction of hyaluronan (Hya) with oppositely charged surfactants. Three representatives of surfactants, namely cetyltrimethylammonium bromide, chloride and p-toluensulfonate (CTAB, CTAC, CTAT), were selected for comparison. The method of rheology was used as a crucial one in this research. The fact that the system of Hya-CTAT forms the most rigid hydrogels has been proved. Higher molecular weight of polymer has also direct influence on the volume and stiffness of the hydrogels. The methods of preparation were compared as well. Mixing the stock solutions of entry components appeard to be the most suitable. The final results indicate that studied gels are to a certain extent competitive. Incorporation of hyaluronan into their structure is desirable with respect to its biological activity. This offers a potential usage of these substances in the field of medical applications.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10403 - Physical chemistry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů