High resolution gold printed electrodes for cell culture monitoring by OECT transistors
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F18%3APU128541" target="_blank" >RIV/00216305:26310/18:PU128541 - isvavai.cz</a>
Výsledek na webu
<a href="http://www.jku.at/conferences/content/e216103/e220127" target="_blank" >http://www.jku.at/conferences/content/e216103/e220127</a>
DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
High resolution gold printed electrodes for cell culture monitoring by OECT transistors
Popis výsledku v původním jazyce
The organic electrochemical transistor (OECT) has a potential for development of innovative biomedical devices. The cultivation of cells in vitro is potentially powerful tool for investigation of drug interaction with the organism for treatment and toxicity testing. In our work, microplate with multi-electrode array of OECTs fabricated by ink-jet technique with gold printed interdigital electrodes and screen printed or spin coated PEDOT:PSS was developed. The high-resolution gold printed electrode up to 55 µm channel length was achieved. The transconductance above 6 mS and time constant 20 ms (frequency up to 50 Hz) were achieved (see Fig. 1). The biocompatibility of 6 commercially available PEDOT:PSS inks and 4 representative semiconductors for utilization in the OECT were tested with 3T3 fibroblasts and murine cardiomyocytes. The developed sensor platforms were used for electrical stimulation and synchronization of beating cardiomyocytes.
Název v anglickém jazyce
High resolution gold printed electrodes for cell culture monitoring by OECT transistors
Popis výsledku anglicky
The organic electrochemical transistor (OECT) has a potential for development of innovative biomedical devices. The cultivation of cells in vitro is potentially powerful tool for investigation of drug interaction with the organism for treatment and toxicity testing. In our work, microplate with multi-electrode array of OECTs fabricated by ink-jet technique with gold printed interdigital electrodes and screen printed or spin coated PEDOT:PSS was developed. The high-resolution gold printed electrode up to 55 µm channel length was achieved. The transconductance above 6 mS and time constant 20 ms (frequency up to 50 Hz) were achieved (see Fig. 1). The biocompatibility of 6 commercially available PEDOT:PSS inks and 4 representative semiconductors for utilization in the OECT were tested with 3T3 fibroblasts and murine cardiomyocytes. The developed sensor platforms were used for electrical stimulation and synchronization of beating cardiomyocytes.
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
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OECD FORD obor
10403 - Physical chemistry
Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2018
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů