Hysteresis during heating and cooling of hyaluronan solutions in water observed by means of ultrasound velocimetry

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F20%3APU137633" target="_blank" >RIV/00216305:26310/20:PU137633 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0141813020348170" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0141813020348170</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijbiomac.2020.10.165" target="_blank" >10.1016/j.ijbiomac.2020.10.165</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Hysteresis during heating and cooling of hyaluronan solutions in water observed by means of ultrasound velocimetry

Popis výsledku v původním jazyce

Ultrasound velocity was measured in hyaluronan solutions of various compositions at different temperatures. The velocity dependence on hyaluronan concentration at constant temperature (25 °C) was linear both in water and in 0.15 M NaCl regardless of hyaluronan molecular weight, confirming diluted-solution behavior. During cyclic heating and cooling, hysteresis on the temperature dependence of ultrasound velocity was observed in the range 30–55 °C in aqueous solutions for all molecular weights. In NaCl solutions, the hysteresis was suppressed and, in contrast to solutions in water where the velocity demonstrated a local maximum with temperature, the velocity decreased with increasing temperature. These findings were attributed to slow and hydration-linked hyaluronan conformation transitions during cooling in water, which were suppressed by the presence of salt, which makes hyaluronan's coiled conformation more compact.

Název v anglickém jazyce

Hysteresis during heating and cooling of hyaluronan solutions in water observed by means of ultrasound velocimetry

Popis výsledku anglicky

Ultrasound velocity was measured in hyaluronan solutions of various compositions at different temperatures. The velocity dependence on hyaluronan concentration at constant temperature (25 °C) was linear both in water and in 0.15 M NaCl regardless of hyaluronan molecular weight, confirming diluted-solution behavior. During cyclic heating and cooling, hysteresis on the temperature dependence of ultrasound velocity was observed in the range 30–55 °C in aqueous solutions for all molecular weights. In NaCl solutions, the hysteresis was suppressed and, in contrast to solutions in water where the velocity demonstrated a local maximum with temperature, the velocity decreased with increasing temperature. These findings were attributed to slow and hydration-linked hyaluronan conformation transitions during cooling in water, which were suppressed by the presence of salt, which makes hyaluronan's coiled conformation more compact.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10403 - Physical chemistry

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

ISSN

0141-8130

e-ISSN

1879-0003

Svazek periodika

165

Číslo periodika v rámci svazku

Part B

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

2419-2424

Kód UT WoS článku

000600773500076

EID výsledku v databázi Scopus

2-s2.0-85094606747