The underexplored role of diverse stress factors in microbial biopolymer synthesis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F21%3APU140377" target="_blank" >RIV/00216305:26310/21:PU140377 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0960852421001061" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0960852421001061</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.biortech.2021.124767" target="_blank" >10.1016/j.biortech.2021.124767</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The underexplored role of diverse stress factors in microbial biopolymer synthesis

Popis výsledku v původním jazyce

Polyhydroxyalkanoates (PHA) are microbial polyesters which, apart from their primary storage role, enhance the stress robustness of PHA accumulating cells against various stressors. PHA also represent interesting alternatives to petrochemical polymers, which can be produced from renewable resources employing approaches of microbial biotechnology. During biotechnological processes, bacterial cells are exposed to various stressor factors such as fluctuations in temperature, osmolarity, pH-value, elevated pressure or the presence of microbial inhibitors. This review summarizes how PHA helps microbial cells to cope with biotechnological process-relevant stressors and, vice versa, how various stress conditions can affect PHA production processes. The review suggests a fundamentally new strategy for PHA production: the fine-tuned exposure to selected stressors, which might be used to boost PHA production and even to tailor their structure.

Název v anglickém jazyce

The underexplored role of diverse stress factors in microbial biopolymer synthesis

Popis výsledku anglicky

Polyhydroxyalkanoates (PHA) are microbial polyesters which, apart from their primary storage role, enhance the stress robustness of PHA accumulating cells against various stressors. PHA also represent interesting alternatives to petrochemical polymers, which can be produced from renewable resources employing approaches of microbial biotechnology. During biotechnological processes, bacterial cells are exposed to various stressor factors such as fluctuations in temperature, osmolarity, pH-value, elevated pressure or the presence of microbial inhibitors. This review summarizes how PHA helps microbial cells to cope with biotechnological process-relevant stressors and, vice versa, how various stress conditions can affect PHA production processes. The review suggests a fundamentally new strategy for PHA production: the fine-tuned exposure to selected stressors, which might be used to boost PHA production and even to tailor their structure.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

20801 - Environmental biotechnology

Projekt

<a href="/cs/project/GA19-20697S" target="_blank" >GA19-20697S: Řízená evoluce bakterií produkujících polyhydroxyalkanoáty</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BIORESOURCE TECHNOLOGY

ISSN

0960-8524

e-ISSN

1873-2976

Svazek periodika

326

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

12

Strana od-do

1-12

Kód UT WoS článku

000620172900004

EID výsledku v databázi Scopus

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