Bioeconomic polyhydroxyalkanoate (PHA) manufacturing, and factors boosting PHA biosynthesis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F19%3APU136098" target="_blank" >RIV/00216305:26310/19:PU136098 - isvavai.cz</a>

Výsledek na webu

<a href="https://reader.elsevier.com/reader/sd/pii/S0168165619301920?token=6C29D68B18EB12E6623BF0303ABD915EB3654003F439A36604C39FBE512E5ED115DDF4DD17D75EBF1078F47C0023EE9D" target="_blank" >https://reader.elsevier.com/reader/sd/pii/S0168165619301920?token=6C29D68B18EB12E6623BF0303ABD915EB3654003F439A36604C39FBE512E5ED115DDF4DD17D75EBF1078F47C0023EE9D</a>

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Bioeconomic polyhydroxyalkanoate (PHA) manufacturing, and factors boosting PHA biosynthesis

Popis výsledku v původním jazyce

Several steps of the process chain to biosynthesize microbialpolyhydroxyalkanoate (PHA) biopolyesters need to be consideredin order to make these auspicious biopolyesters quantitatively andqualitatively competitive on the global plastic market. Selection,adaptation and genetic modification of microbial strains, feedstocksupply, bioreactor design and process regime, and product recov-ery require optimization. Especially the application of robust, fastgrowing and highly productive microbial species for PHA pro-duction using inexpensive carbon-rich feedstocks has become afrequently used strategy towards economically feasible PHA pro-duction. During biosynthesis, exogenous stress factors triggeringPHA accumulation in microbial biomass play a still underestimatedrole. As recently revealed, presence of PHA helps cells to mitigatethe harmful effects of diverse stress factors like osmotic imbal-ance, oxidative challenge or UV-radiation; biotechnologically, onecan deliberately expose bacterial cells to such st

Název v anglickém jazyce

Bioeconomic polyhydroxyalkanoate (PHA) manufacturing, and factors boosting PHA biosynthesis

Popis výsledku anglicky

Several steps of the process chain to biosynthesize microbialpolyhydroxyalkanoate (PHA) biopolyesters need to be consideredin order to make these auspicious biopolyesters quantitatively andqualitatively competitive on the global plastic market. Selection,adaptation and genetic modification of microbial strains, feedstocksupply, bioreactor design and process regime, and product recov-ery require optimization. Especially the application of robust, fastgrowing and highly productive microbial species for PHA pro-duction using inexpensive carbon-rich feedstocks has become afrequently used strategy towards economically feasible PHA pro-duction. During biosynthesis, exogenous stress factors triggeringPHA accumulation in microbial biomass play a still underestimatedrole. As recently revealed, presence of PHA helps cells to mitigatethe harmful effects of diverse stress factors like osmotic imbal-ance, oxidative challenge or UV-radiation; biotechnologically, onecan deliberately expose bacterial cells to such st

Druh

O - Ostatní výsledky

CEP obor

—

OECD FORD obor

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů