Skin protecting activity of microbial extracts

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F21%3APU142569" target="_blank" >RIV/00216305:26310/21:PU142569 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Skin protecting activity of microbial extracts

Popis výsledku v původním jazyce

Microalgae and red yeast extracts contain a broad spectrum of compounds, which could serve as an alternative to conventional nutrient sour-ce. Moreover, the extracts contain antioxidants and can provide nutrition and protection of the skin.Presented work aims at preparation and characterization of liposome particles with complex aqueous and oil extracts of microbial origin. Active compounds as well as antioxidant activity and SPF were determined by HPLC and spectrophotometry. Most promising extracts were packed into liposome and PHB-liposome particles. Prepared particles were characterized by their encapsulation efficiency, particle size and poly-dispersity index together with colloidal stability. Antimicrobial activity was tested against S. epidermidis and E. coli. Prepared extracts and particles were evaluated by MTT assay on human keratinocytes HaCaT cell line whether they alter cell viability.Micro- and nanoparticles with encapsulated antioxidant and antimicrobial active compounds can enhance the

Název v anglickém jazyce

Skin protecting activity of microbial extracts

Popis výsledku anglicky

Microalgae and red yeast extracts contain a broad spectrum of compounds, which could serve as an alternative to conventional nutrient sour-ce. Moreover, the extracts contain antioxidants and can provide nutrition and protection of the skin.Presented work aims at preparation and characterization of liposome particles with complex aqueous and oil extracts of microbial origin. Active compounds as well as antioxidant activity and SPF were determined by HPLC and spectrophotometry. Most promising extracts were packed into liposome and PHB-liposome particles. Prepared particles were characterized by their encapsulation efficiency, particle size and poly-dispersity index together with colloidal stability. Antimicrobial activity was tested against S. epidermidis and E. coli. Prepared extracts and particles were evaluated by MTT assay on human keratinocytes HaCaT cell line whether they alter cell viability.Micro- and nanoparticles with encapsulated antioxidant and antimicrobial active compounds can enhance the

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů