Significant bactericidal effects of gelatin nanofibers modified with oxidized cellulose

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F14%3APU110681" target="_blank" >RIV/00216305:26620/14:PU110681 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Significant bactericidal effects of gelatin nanofibers modified with oxidized cellulose

Popis výsledku v původním jazyce

This work is focused on the preparation of gelatin nanofibers that are doped with salt of oxidized cellulose. Gelatin is a mixture of proteins which is obtained by partial hydrolysis of natural protein - collagen. Gelatin is a biocompatible, biodegradable material with high absorption capacity. Oxidized cellulose and its salts are also biocompatible, biodegradable and they have antibacterial and hemostatic effects. In this study we developed a new material which combine the properties both of them. Nanofibers with unique bactericide efficiency was obtained via electrospinning process. Chemical composition of the fibers has been studied by ATR-FTIR spectroscopy and EDX elemental analysis. The results of these analysis confirmed the presence of salt of oxidized cellulose in prepared mats. Diameter of nanofibers and their morphology were determined by scanning electron microscopy (SEM). Bactericidal effect was examined by the method of chemical bioluminescence on modified bacterial strain

Název v anglickém jazyce

Significant bactericidal effects of gelatin nanofibers modified with oxidized cellulose

Popis výsledku anglicky

This work is focused on the preparation of gelatin nanofibers that are doped with salt of oxidized cellulose. Gelatin is a mixture of proteins which is obtained by partial hydrolysis of natural protein - collagen. Gelatin is a biocompatible, biodegradable material with high absorption capacity. Oxidized cellulose and its salts are also biocompatible, biodegradable and they have antibacterial and hemostatic effects. In this study we developed a new material which combine the properties both of them. Nanofibers with unique bactericide efficiency was obtained via electrospinning process. Chemical composition of the fibers has been studied by ATR-FTIR spectroscopy and EDX elemental analysis. The results of these analysis confirmed the presence of salt of oxidized cellulose in prepared mats. Diameter of nanofibers and their morphology were determined by scanning electron microscopy (SEM). Bactericidal effect was examined by the method of chemical bioluminescence on modified bacterial strain

Druh

O - Ostatní výsledky

CEP obor

CD - Makromolekulární chemie

OECD FORD obor

—

Projekt

<a href="/cs/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: CEITEC - central european institute of technology</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů