Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F14%3APU111294" target="_blank" >RIV/00216305:26620/14:PU111294 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ceramint.2014.06.071" target="_blank" >http://dx.doi.org/10.1016/j.ceramint.2014.06.071</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ceramint.2014.06.071" target="_blank" >10.1016/j.ceramint.2014.06.071</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery

Popis výsledku v původním jazyce

Nowadays, diffusion through scaffold and tissue usually limits transport, and forms potentially hypoxic regions. Several methods are used for preparation of 3D hydroxyapatite scaffolds, however, production of a scaffold including porous hollow fibers for nutrition delivery is difficult and expensive. In this study, we describe an easy and inexpensive method to create 3D hydroxyapatite structure containing porous hollow fibers via microtemplating. The fibers which are assembled into 3D scaffold and sintered, contain asymmetric membrane walls with flux suitable for nutrient delivery. These hollow fibers have good mesenchymal stem cell adhesion showing that the presented method has no negative influence on cell cytocompatibility. The proposed straightforward method for building 3D structures containing porous hollow fibers for nutritions can be suitable for in vitro bioreactors studies as well as for production tissue engineered or in vivo prepared bone grafts.

Název v anglickém jazyce

Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery

Popis výsledku anglicky

Nowadays, diffusion through scaffold and tissue usually limits transport, and forms potentially hypoxic regions. Several methods are used for preparation of 3D hydroxyapatite scaffolds, however, production of a scaffold including porous hollow fibers for nutrition delivery is difficult and expensive. In this study, we describe an easy and inexpensive method to create 3D hydroxyapatite structure containing porous hollow fibers via microtemplating. The fibers which are assembled into 3D scaffold and sintered, contain asymmetric membrane walls with flux suitable for nutrient delivery. These hollow fibers have good mesenchymal stem cell adhesion showing that the presented method has no negative influence on cell cytocompatibility. The proposed straightforward method for building 3D structures containing porous hollow fibers for nutritions can be suitable for in vitro bioreactors studies as well as for production tissue engineered or in vivo prepared bone grafts.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20504 - Ceramics

Projekt

<a href="/cs/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: CEITEC - central european institute of technology</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Ceramics International

ISSN

0272-8842

e-ISSN

1873-3956

Svazek periodika

40

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

14793-14799

Kód UT WoS článku

000341343300032

EID výsledku v databázi Scopus

2-s2.0-84905910104