Solvent free synthesis and structural evaluation of polyurethane films based on poly(ethylene glycol) and poly(caprolactone)
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F16%3APU118622" target="_blank" >RIV/00216305:26620/16:PU118622 - isvavai.cz</a>
Výsledek na webu
<a href="http://www.expresspolymlett.com/index.html?tartalom=content.php&year=2016&number=6&kodnumber=1" target="_blank" >http://www.expresspolymlett.com/index.html?tartalom=content.php&year=2016&number=6&kodnumber=1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3144/expresspolymlett.2016.46" target="_blank" >10.3144/expresspolymlett.2016.46</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Solvent free synthesis and structural evaluation of polyurethane films based on poly(ethylene glycol) and poly(caprolactone)
Popis výsledku v původním jazyce
Biodegradable amphiphilic polyurethane films (bio-PUs) were synthesized by solvent free polyaddition reaction of hydrophilic poly(ethylene glycol) (PEG) and hydrophobic poly(caprolactone) (PCL) as macrodiols with hexamethylene diisocyanate. Samples were subsequently heat cured in order to obtain 3D crosslinked structure. Different PCL/PEG ratios allowed controlling the toughness of the resulting bio-PUs. Significant enhancement of Young’s modulus, strength and elongation at break was observed at a PCL/PEG molar ratio above 3. The change in the bio-PU mechanical behavior was ascribed to the formation of crystalline PCL domains in the bio-PU network. The presence of PEG increased both the ability to absorb water and the rate of hydrolytic degradation, while PCL increased the cell viability. Prepared solvent free bio-PUs may advantageously be used in medicine as elastic resorbable material applicable against post-surgical adhesions.
Název v anglickém jazyce
Solvent free synthesis and structural evaluation of polyurethane films based on poly(ethylene glycol) and poly(caprolactone)
Popis výsledku anglicky
Biodegradable amphiphilic polyurethane films (bio-PUs) were synthesized by solvent free polyaddition reaction of hydrophilic poly(ethylene glycol) (PEG) and hydrophobic poly(caprolactone) (PCL) as macrodiols with hexamethylene diisocyanate. Samples were subsequently heat cured in order to obtain 3D crosslinked structure. Different PCL/PEG ratios allowed controlling the toughness of the resulting bio-PUs. Significant enhancement of Young’s modulus, strength and elongation at break was observed at a PCL/PEG molar ratio above 3. The change in the bio-PU mechanical behavior was ascribed to the formation of crystalline PCL domains in the bio-PU network. The presence of PEG increased both the ability to absorb water and the rate of hydrolytic degradation, while PCL increased the cell viability. Prepared solvent free bio-PUs may advantageously be used in medicine as elastic resorbable material applicable against post-surgical adhesions.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10404 - Polymer science
Návaznosti výsledku
Projekt
<a href="/cs/project/LQ1601" target="_blank" >LQ1601: CEITEC 2020</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2016
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
EXPRESS POLYM LETT
ISSN
1788-618X
e-ISSN
—
Svazek periodika
neuveden
Číslo periodika v rámci svazku
6
Stát vydavatele periodika
HU - Maďarsko
Počet stran výsledku
14
Strana od-do
479-492
Kód UT WoS článku
000373563000006
EID výsledku v databázi Scopus
2-s2.0-84962428254