Strength degradation, phase and morphological changes of calcium phosphate scaffolds in acidic environment simulating osteoclastic activity

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F18%3APU129452" target="_blank" >RIV/00216305:26620/18:PU129452 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.esb2018maastricht.org/resources/media/Programme/ESB_2018_Abstract__Proceedings_4.pdf" target="_blank" >http://www.esb2018maastricht.org/resources/media/Programme/ESB_2018_Abstract__Proceedings_4.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Strength degradation, phase and morphological changes of calcium phosphate scaffolds in acidic environment simulating osteoclastic activity

Popis výsledku v původním jazyce

Resorbable porous ceramic materials with customized shape are promising category of materials for healing of bone defects with critical size1. Resorption rate of the ceramic structure must correspond to the bone tissue regeneration. The only mechanism of degradation of sintered ceramic materials in a human body is via dissolution under acidic conditions produced by osteoclastic cells2. Dissolution of the ceramics correspond to changes in its mechanical strength. In our research we described structural and mechanical changes of different types of calcium phosphate ceramic materials under acidic conditions simulating osteoclastic activity. Results will help to develop bioceramic scaffolds with controlled resorption rate with good mechanical strength during healing period.

Název v anglickém jazyce

Strength degradation, phase and morphological changes of calcium phosphate scaffolds in acidic environment simulating osteoclastic activity

Popis výsledku anglicky

Resorbable porous ceramic materials with customized shape are promising category of materials for healing of bone defects with critical size1. Resorption rate of the ceramic structure must correspond to the bone tissue regeneration. The only mechanism of degradation of sintered ceramic materials in a human body is via dissolution under acidic conditions produced by osteoclastic cells2. Dissolution of the ceramics correspond to changes in its mechanical strength. In our research we described structural and mechanical changes of different types of calcium phosphate ceramic materials under acidic conditions simulating osteoclastic activity. Results will help to develop bioceramic scaffolds with controlled resorption rate with good mechanical strength during healing period.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

20504 - Ceramics

Projekt

<a href="/cs/project/LM2015041" target="_blank" >LM2015041: CEITEC Nano</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů