Imaging of soft tissues by laser-induced breakdown spectroscopy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F21%3APU142599" target="_blank" >RIV/00216305:26620/21:PU142599 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Imaging of soft tissues by laser-induced breakdown spectroscopy

Popis výsledku v původním jazyce

Laser-induced breakdown spectroscopy (LIBS) is a micro-destructive method with extensive possibilities of elemental analysis. It is a type of optical emission spectroscopy using a pulsed laser (typically an Nd-YAG). The laser pulse is focused into a tight spot inducing high-intensity irradiation of the material and its ablation; consequently, a luminous micro-plasma is created. The parameters of a laser pulse play a crucial role in the laser-matter interaction and contribute to the complex phenomenon of plasma formation and its thermodynamic properties. Optimizing the analytical methodology is a necessary and crucial step, especially in the case of high-throughput elemental imaging of biological tissues, such as soft tissues. In this study, we built on our recent work [1] where the challenging LIBS analysis of soft tissue, namely murine kidneys, analysis was addressed. The article brings thorough optimization of the experimental setup to reach the best possible performance in the trade-off between se

Název v anglickém jazyce

Imaging of soft tissues by laser-induced breakdown spectroscopy

Popis výsledku anglicky

Laser-induced breakdown spectroscopy (LIBS) is a micro-destructive method with extensive possibilities of elemental analysis. It is a type of optical emission spectroscopy using a pulsed laser (typically an Nd-YAG). The laser pulse is focused into a tight spot inducing high-intensity irradiation of the material and its ablation; consequently, a luminous micro-plasma is created. The parameters of a laser pulse play a crucial role in the laser-matter interaction and contribute to the complex phenomenon of plasma formation and its thermodynamic properties. Optimizing the analytical methodology is a necessary and crucial step, especially in the case of high-throughput elemental imaging of biological tissues, such as soft tissues. In this study, we built on our recent work [1] where the challenging LIBS analysis of soft tissue, namely murine kidneys, analysis was addressed. The article brings thorough optimization of the experimental setup to reach the best possible performance in the trade-off between se

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10406 - Analytical chemistry

Projekt

<a href="/cs/project/GJ20-19526Y" target="_blank" >GJ20-19526Y: Procesy laserové ablace měkkých tkání a následného vývoje laserem buzeného plazmatu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů