Time-lapse Quantitative Phase Imaging for the Study of Cell Migration

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F23%3APU148373" target="_blank" >RIV/00216305:26620/23:PU148373 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Time-lapse Quantitative Phase Imaging for the Study of Cell Migration

Popis výsledku v původním jazyce

Quantitative Phase Imaging (QPI) is a powerful label-free technique widely used to study the dynamic processes of living cells in real-time. QPI in time-lapse microscopy offers several benefits, including high sensitivity, low phototoxicity, high spatial and temporal resolution, and quantitative measurements of cellular morphology and mechanical properties. In this presentation, we will discuss using of QPI to study cell migration, a fundamental biological process that is critical for tissue development and repair. We will demonstrate how QPI can provide detailed insights into the dynamics of cell migration, including the speed of cell movement, the direction of migration, and the evaluation of the migrastatic drugs, or the way of migration in extracellular matrices. Additionally, we will show how QPI can be used to quantify cellular parameters such as cell dry mass, area, perimeter, migration index, or Euclidean distance. Our results demonstrate the potential of QPI in time-lapse microscopy as a powerful tool for studying cell migration and other dynamic processes in living cells.

Název v anglickém jazyce

Time-lapse Quantitative Phase Imaging for the Study of Cell Migration

Popis výsledku anglicky

Quantitative Phase Imaging (QPI) is a powerful label-free technique widely used to study the dynamic processes of living cells in real-time. QPI in time-lapse microscopy offers several benefits, including high sensitivity, low phototoxicity, high spatial and temporal resolution, and quantitative measurements of cellular morphology and mechanical properties. In this presentation, we will discuss using of QPI to study cell migration, a fundamental biological process that is critical for tissue development and repair. We will demonstrate how QPI can provide detailed insights into the dynamics of cell migration, including the speed of cell movement, the direction of migration, and the evaluation of the migrastatic drugs, or the way of migration in extracellular matrices. Additionally, we will show how QPI can be used to quantify cellular parameters such as cell dry mass, area, perimeter, migration index, or Euclidean distance. Our results demonstrate the potential of QPI in time-lapse microscopy as a powerful tool for studying cell migration and other dynamic processes in living cells.

Druh

A - Audiovizuální tvorba

CEP obor

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OECD FORD obor

10306 - Optics (including laser optics and quantum optics)

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

ISBN

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Místo vydání

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Název nakladatele resp. objednatele

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Verze

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Identifikační číslo nosiče

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