Fabrication of customized open-cell titanium foams by direct foaming for biomedical applications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F24%3APU152322" target="_blank" >RIV/00216305:26620/24:PU152322 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/24:00137424 RIV/00216208:11320/24:10494307

Výsledek na webu

<a href="https://www.webofscience.com/wos/woscc/full-record/WOS:001324667400001" target="_blank" >https://www.webofscience.com/wos/woscc/full-record/WOS:001324667400001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jmrt.2024.09.136" target="_blank" >10.1016/j.jmrt.2024.09.136</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Fabrication of customized open-cell titanium foams by direct foaming for biomedical applications

Popis výsledku v původním jazyce

Titanium (Ti) foams offer a promising alternative for bone reconstruction and repair due to their high porosity and lower stiffness compared to solid metals, which improves in vivo osseointegration by reducing the stress shielding effect and allowing bone ingrowth. In this work, customized Ti foams were successfully fabricated for the first time at room temperature using a direct foaming method. Ti powder suspension with a water-soluble surfactant and environmentally friendly thickener was foamed by mechanical stirring. Then, 3D-printed moulds were utilized to achieve near-net shape foams, which were subsequently consolidated by sintering, thus avoiding the need for complex processing of molten Ti. The resulting Ti foams exhibited a cancellous-like open-cell structure, high porosity (> 80%), and a five times higher effective surface area than a 3D Ti mesh with a primitive cubic-based cell fabricated by additive manufacturing. In addition, the Ti foams exhibited similar mechanical properties to cancellous bone and facilitated the adhesion, proliferation, and maturation of human osteoblasts in vitro.

Název v anglickém jazyce

Fabrication of customized open-cell titanium foams by direct foaming for biomedical applications

Popis výsledku anglicky

Titanium (Ti) foams offer a promising alternative for bone reconstruction and repair due to their high porosity and lower stiffness compared to solid metals, which improves in vivo osseointegration by reducing the stress shielding effect and allowing bone ingrowth. In this work, customized Ti foams were successfully fabricated for the first time at room temperature using a direct foaming method. Ti powder suspension with a water-soluble surfactant and environmentally friendly thickener was foamed by mechanical stirring. Then, 3D-printed moulds were utilized to achieve near-net shape foams, which were subsequently consolidated by sintering, thus avoiding the need for complex processing of molten Ti. The resulting Ti foams exhibited a cancellous-like open-cell structure, high porosity (> 80%), and a five times higher effective surface area than a 3D Ti mesh with a primitive cubic-based cell fabricated by additive manufacturing. In addition, the Ti foams exhibited similar mechanical properties to cancellous bone and facilitated the adhesion, proliferation, and maturation of human osteoblasts in vitro.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20501 - Materials engineering

Projekt

<a href="/cs/project/NW24-10-00195" target="_blank" >NW24-10-00195: Personalizovaná rekonstrukce kosti s rychlou osseointegrací a antibakteriální titanové implantáty po chirurgické resekci osteosarkomu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Materials Research and Technology

ISSN

2238-7854

e-ISSN

2214-0697

Svazek periodika

33

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

BR - Brazilská federativní republika

Počet stran výsledku

11

Strana od-do

1704-1714

Kód UT WoS článku

001324667400001

EID výsledku v databázi Scopus

2-s2.0-85204732832