Virus Enhanced Microrobots for Biofilm Eradication

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F26%3A0199233" target="_blank" >RIV/00216305:26620/26:0199233 - isvavai.cz</a>

Výsledek na webu

<a href="https://advanced.onlinelibrary.wiley.com/doi/epdf/10.1002/adma.202508299?getft_integrator=clarivate&src=getftr&utm_source=clarivate" target="_blank" >https://advanced.onlinelibrary.wiley.com/doi/epdf/10.1002/adma.202508299?getft_integrator=clarivate&src=getftr&utm_source=clarivate</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/adma.202508299" target="_blank" >10.1002/adma.202508299</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Virus Enhanced Microrobots for Biofilm Eradication

Popis výsledku v původním jazyce

Biofilms pose significant challenges in biomedical, industrial, and environmental applications due to their inherent resistance to antimicrobial agents. This study introduced an innovative and effective strategy for biofilm eradication by employing virus-conjugated microrobots (virus@microbots). These biofunctionalized microrobots are synthesized via the hydrothermal method, followed by the functionalization of the viruses. The synergy of microrobots' active movement and the virus's specificity boosted biofilm removal by enabling targeted binding, penetration, and effective delivery into the biofilm matrices. Additionally, compared to microrobots alone, virus@microbots significantly accelerated and refined the process. By integrating biological specificity with magnetic responsiveness, this approach demonstrated the efficacy of virus@microbotsas as a viable antibacterial strategy for biofilm elimination, offering a promising antibacterial platform for combating biofilm-associated infections. Future research should focus on optimizing microrobot design and viral conjugation protocols to enhance scalability and therapeutic specificity, paving the way for clinical translation and broader applications in infection control.

Název v anglickém jazyce

Virus Enhanced Microrobots for Biofilm Eradication

Popis výsledku anglicky

Biofilms pose significant challenges in biomedical, industrial, and environmental applications due to their inherent resistance to antimicrobial agents. This study introduced an innovative and effective strategy for biofilm eradication by employing virus-conjugated microrobots (virus@microbots). These biofunctionalized microrobots are synthesized via the hydrothermal method, followed by the functionalization of the viruses. The synergy of microrobots' active movement and the virus's specificity boosted biofilm removal by enabling targeted binding, penetration, and effective delivery into the biofilm matrices. Additionally, compared to microrobots alone, virus@microbots significantly accelerated and refined the process. By integrating biological specificity with magnetic responsiveness, this approach demonstrated the efficacy of virus@microbotsas as a viable antibacterial strategy for biofilm elimination, offering a promising antibacterial platform for combating biofilm-associated infections. Future research should focus on optimizing microrobot design and viral conjugation protocols to enhance scalability and therapeutic specificity, paving the way for clinical translation and broader applications in infection control.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

21000 - Nano-technology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2026

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ADVANCED MATERIALS

ISSN

0935-9648

e-ISSN

1521-4095

Svazek periodika

38

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

14

Strana od-do

—

Kód UT WoS článku

001586392800001

EID výsledku v databázi Scopus

2-s2.0-105018313084