High-grade oncocytic tumour (HOT) of kidney in a patient with tuberous sclerosis complex
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F19%3A10395932" target="_blank" >RIV/00669806:_____/19:10395932 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00216208:11140/19:10395932
Výsledek na webu
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=GeIP5xvTsl" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=GeIP5xvTsl</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/his.13876" target="_blank" >10.1111/his.13876</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
High-grade oncocytic tumour (HOT) of kidney in a patient with tuberous sclerosis complex
Popis výsledku v původním jazyce
Sir: High-grade oncocytic tumour (HOT) was recently proposed as a novel renal entity that is currently not included in the World Health Organisation (WHO) classification.1 The first published series by He et al. included 14 tumours, collected from multiple institutional files.1 Recently, Chen et al. reported another series of seven morphologically very similar tumours that they designated 'sporadic renal cell carcinomas with eosinophilic and vacuolated cytoplasm'2 Using next-generation sequenncing they identified somatic inactivating mutations of TSC2 in three of five tumours tested or activating mutations of MTOR (in two of five tumours tested).1 We wishto report a novel example of this emerging entity which, in contrast to the cases reported so far, was see in a patient with a tuberous sclerosis complex(TSC). A 48-year-old female patient with a knows TSC presented with bilateral renal masses on routine ultrasound screening. The patient's clinical manifestations of TSC included facial rash, nail changes and bilateral renal masses without a history of seizures or haematuria.
Název v anglickém jazyce
High-grade oncocytic tumour (HOT) of kidney in a patient with tuberous sclerosis complex
Popis výsledku anglicky
Sir: High-grade oncocytic tumour (HOT) was recently proposed as a novel renal entity that is currently not included in the World Health Organisation (WHO) classification.1 The first published series by He et al. included 14 tumours, collected from multiple institutional files.1 Recently, Chen et al. reported another series of seven morphologically very similar tumours that they designated 'sporadic renal cell carcinomas with eosinophilic and vacuolated cytoplasm'2 Using next-generation sequenncing they identified somatic inactivating mutations of TSC2 in three of five tumours tested or activating mutations of MTOR (in two of five tumours tested).1 We wishto report a novel example of this emerging entity which, in contrast to the cases reported so far, was see in a patient with a tuberous sclerosis complex(TSC). A 48-year-old female patient with a knows TSC presented with bilateral renal masses on routine ultrasound screening. The patient's clinical manifestations of TSC included facial rash, nail changes and bilateral renal masses without a history of seizures or haematuria.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
30109 - Pathology
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2019
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Histopathology
ISSN
0309-0167
e-ISSN
—
Svazek periodika
75
Číslo periodika v rámci svazku
3
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
3
Strana od-do
440-442
Kód UT WoS článku
000481443100017
EID výsledku v databázi Scopus
2-s2.0-85068532262