Adjustment of Insulin Pump Settings in Type 1 Diabetes Management: Advisor Pro Device Compared to Physicians' Recommendations

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F22%3A10445471" target="_blank" >RIV/00669806:_____/22:10445471 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11140/22:10445471

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=pIH1Xvf7Wy" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=pIH1Xvf7Wy</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/1932296820965561" target="_blank" >10.1177/1932296820965561</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Adjustment of Insulin Pump Settings in Type 1 Diabetes Management: Advisor Pro Device Compared to Physicians' Recommendations

Popis výsledku v původním jazyce

Aims: To compare insulin dose adjustments made by physicians to those made by an artificial intelligence-based decision support system, the Advisor Pro, in people with type 1 diabetes (T1D) using an insulin pump and self-monitoring blood glucose (SMBG). Methods: This was a multinational, non-interventional study surveying 17 physicians from 11 countries. Each physician was asked to provide insulin dose adjustments for the settings of the pump including basal rate, carbohydrate-to-insulin ratios (CRs), and correction factors (CFs) for 15 data sets of pumps and SMBG of people with T1D (mean age 18.4 +- 4.8 years; eight females; mean glycated hemoglobin 8.2% +- 1.4% [66 +- 11mmol/mol]). The recommendations were compared among the physicians and between the physicians and the Advisor Pro. The study endpoint was the percentage of comparison points for which there was an agreement on the direction of insulin dose adjustments. Results: The percentage (mean +- SD) of agreement among the physicians on the direction of insulin pump dose adjustments was 51.8% +- 9.2%, 54.2% +- 6.4%, and 49.8% +- 11.6% for the basal, CR, and CF, respectively. The automated recommendations of the Advisor Pro on the direction of insulin dose adjustments were comparable)49.5% +- 6.4%, 55.3% +- 8.7%, and 47.6% +- 14.4% for the basal rate, CR, and CF, respectively(and noninferior to those provided by physicians. The mean absolute difference in magnitude of change between physicians was 17.1% +- 13.1%, 14.6% +- 8.4%, and 23.9% +- 18.6% for the basal, CR, and CF, respectively, and comparable to the Advisor Pro 11.7% +- 9.7%, 10.1% +- 4.5%, and 25.5% +- 19.5%, respectively, significant for basal and CR. Conclusions: Considerable differences in the recommendations for changes in insulin dosing were observed among physicians. Since automated recommendations by the Advisor Pro were similar to those given by physicians, it could be considered a useful tool to manage T1D.

Název v anglickém jazyce

Adjustment of Insulin Pump Settings in Type 1 Diabetes Management: Advisor Pro Device Compared to Physicians' Recommendations

Popis výsledku anglicky

Aims: To compare insulin dose adjustments made by physicians to those made by an artificial intelligence-based decision support system, the Advisor Pro, in people with type 1 diabetes (T1D) using an insulin pump and self-monitoring blood glucose (SMBG). Methods: This was a multinational, non-interventional study surveying 17 physicians from 11 countries. Each physician was asked to provide insulin dose adjustments for the settings of the pump including basal rate, carbohydrate-to-insulin ratios (CRs), and correction factors (CFs) for 15 data sets of pumps and SMBG of people with T1D (mean age 18.4 +- 4.8 years; eight females; mean glycated hemoglobin 8.2% +- 1.4% [66 +- 11mmol/mol]). The recommendations were compared among the physicians and between the physicians and the Advisor Pro. The study endpoint was the percentage of comparison points for which there was an agreement on the direction of insulin dose adjustments. Results: The percentage (mean +- SD) of agreement among the physicians on the direction of insulin pump dose adjustments was 51.8% +- 9.2%, 54.2% +- 6.4%, and 49.8% +- 11.6% for the basal, CR, and CF, respectively. The automated recommendations of the Advisor Pro on the direction of insulin dose adjustments were comparable)49.5% +- 6.4%, 55.3% +- 8.7%, and 47.6% +- 14.4% for the basal rate, CR, and CF, respectively(and noninferior to those provided by physicians. The mean absolute difference in magnitude of change between physicians was 17.1% +- 13.1%, 14.6% +- 8.4%, and 23.9% +- 18.6% for the basal, CR, and CF, respectively, and comparable to the Advisor Pro 11.7% +- 9.7%, 10.1% +- 4.5%, and 25.5% +- 19.5%, respectively, significant for basal and CR. Conclusions: Considerable differences in the recommendations for changes in insulin dosing were observed among physicians. Since automated recommendations by the Advisor Pro were similar to those given by physicians, it could be considered a useful tool to manage T1D.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30202 - Endocrinology and metabolism (including diabetes, hormones)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Diabetes Science and Technology

ISSN

1932-2968

e-ISSN

—

Svazek periodika

16

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

364-372

Kód UT WoS článku

000904126500010

EID výsledku v databázi Scopus

2-s2.0-85093918656