Dvojitá erytrocytaferéza: parametry jakosti deleukotizovaných erytrocytů

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00829951%3A_____%2F05%3A%230000014" target="_blank" >RIV/00829951:_____/05:#0000014 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Double erythrocytapheresis: Quality parameters of two WBC- reduced RBC.

Popis výsledku v původním jazyce

A new apheresis procedure enables the collection of two WBC- reduced RBC units in a single donation. The aim of this study was to evaluate the quality parameters of apheresis WBC- reduced RBC units (A-RBC) including markers of hemolysis and red cells injury. We completed 20 double - erythrocytapheresis with the separator Haemonetics MCS+ and prepared 40 TU WBC ? reduced RBC. We investigated the content of Hb, Ht, WBC count and content of IgA in TU. Free Hb, K+, LDH, lactate, pH and annexin V were analyzed in the day 0 and 40. During the storage time free Hb increasing was higher in A-RBC, no differences in increasing K + value and no change in pH between A -RBC and WB ? RBC were founded. The LDH increasing was higher in A-RBC and correlated to hemolysis in both types of RBC, No correlation of K+ according to free Hb was found.The changes of annexin V were the same in both type of RBC, increase of annexin V levels correlated according to values of free Hb.

Název v anglickém jazyce

Double erythrocytapheresis: Quality parameters of two WBC- reduced RBC.

Popis výsledku anglicky

A new apheresis procedure enables the collection of two WBC- reduced RBC units in a single donation. The aim of this study was to evaluate the quality parameters of apheresis WBC- reduced RBC units (A-RBC) including markers of hemolysis and red cells injury. We completed 20 double - erythrocytapheresis with the separator Haemonetics MCS+ and prepared 40 TU WBC ? reduced RBC. We investigated the content of Hb, Ht, WBC count and content of IgA in TU. Free Hb, K+, LDH, lactate, pH and annexin V were analyzed in the day 0 and 40. During the storage time free Hb increasing was higher in A-RBC, no differences in increasing K + value and no change in pH between A -RBC and WB ? RBC were founded. The LDH increasing was higher in A-RBC and correlated to hemolysis in both types of RBC, No correlation of K+ according to free Hb was found.The changes of annexin V were the same in both type of RBC, increase of annexin V levels correlated according to values of free Hb.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

<a href="/cs/project/NR8015" target="_blank" >NR8015: Multikomponentní aferetické odběry - nový směr v dárcovství krve</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Transfusion and Apheresis Science

ISSN

1473-0502

e-ISSN

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Svazek periodika

33

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

2

Strana od-do

207-208

Kód UT WoS článku

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EID výsledku v databázi Scopus

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