Bezpečnost a účinnost akcelerace rekanalizace střední mozkové tepny pomocí ultrazvuku: výsledky pilotní Thrombotripsy study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F08%3A00016033" target="_blank" >RIV/00843989:_____/08:00016033 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Safety and efficacy of the sonographic acceleration of the middle cerebral artery recanalization: results of the pilot thrombotripsy study

Popis výsledku v původním jazyce

The aim was to demonstrate the safety and efficacy of continuous ultrasound monitoring of the artery occlusion area (sonothrombotripsy) in patients with acute middle cerebral artery (MCA) occlusion. A total of 52 consecutive patients with acute MCA occlusion were included in the thrombotripsy group. Doppler monitoring of the region of occlusion was performed for up to 45 minutes. The control group was created from the NAIS study database. In the Thrombotripsy group, 19 patients (36.5%) had complete recanalization and 27 (51.9%) patients had partial recanalization at one hour after the start of the TCCS monitoring. Higher recanalization rates at 6 and 24 hours after stoke onset were also seen compared to controls (69.2% vs. 7.7% and 92.3% vs. 61.5% complete recanalizations resp., p < 0.05). Independence (mRS 0-2) at day 90 was achieved by 61.5% of the Thrombotripsy patients and 32.7% controls, p < 0.05, OR 1.88 (95% CI = 1.23 ? 2.90).

Název v anglickém jazyce

Safety and efficacy of the sonographic acceleration of the middle cerebral artery recanalization: results of the pilot thrombotripsy study

Popis výsledku anglicky

The aim was to demonstrate the safety and efficacy of continuous ultrasound monitoring of the artery occlusion area (sonothrombotripsy) in patients with acute middle cerebral artery (MCA) occlusion. A total of 52 consecutive patients with acute MCA occlusion were included in the thrombotripsy group. Doppler monitoring of the region of occlusion was performed for up to 45 minutes. The control group was created from the NAIS study database. In the Thrombotripsy group, 19 patients (36.5%) had complete recanalization and 27 (51.9%) patients had partial recanalization at one hour after the start of the TCCS monitoring. Higher recanalization rates at 6 and 24 hours after stoke onset were also seen compared to controls (69.2% vs. 7.7% and 92.3% vs. 61.5% complete recanalizations resp., p < 0.05). Independence (mRS 0-2) at day 90 was achieved by 61.5% of the Thrombotripsy patients and 32.7% controls, p < 0.05, OR 1.88 (95% CI = 1.23 ? 2.90).

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Ultrasound in Medicine & Biology

ISSN

0301-5629

e-ISSN

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Svazek periodika

34

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

8

Strana od-do

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Kód UT WoS článku

000260611000010

EID výsledku v databázi Scopus

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