Safety and efficacy of sono-thrombolysis and sono-thrombotripsy in patiens with acute occlusion of modele cerebrál Artury and healthy volunteers

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F08%3A10224575" target="_blank" >RIV/61989592:15110/08:10224575 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Safety and efficacy of sono-thrombolysis and sono-thrombotripsy in patiens with acute occlusion of modele cerebrál Artury and healthy volunteers

Popis výsledku v původním jazyce

The aim was to demonstrate the safety and efficacy of continuous ultrasound monitoring of the artery occlusion area (sonotrombotripsy) in patients with acute middle cerebral artery (MCA) occlusion. A total of 52concecutive patients with acute MCA occlusion were included in the thrombotripsy group. Doppler monitoring of the region of occlusion was performed for up to 45 min. The control group was created from the NAIS study database. Patients were matched for their vascular status, age, sex, artery occlusion, NIHSS at admission, rt-PA treatment and time to the first ultrasound examinations. The number of recanalized arteries at 6 and 24 h after the onset of symptoms, the number of independent patients (mRS 0-2 versus 3-6) after 90 d, and the number of serious adverse events were statistically evaluated. In the thrombotripsy group, 19 patients (36.5%) had complete recanalization and 27 (51.9%) patients had partial recanalization at 1 h after the start of the TCCS monitoring. Higher recan

Název v anglickém jazyce

Safety and efficacy of sono-thrombolysis and sono-thrombotripsy in patiens with acute occlusion of modele cerebrál Artury and healthy volunteers

Popis výsledku anglicky

The aim was to demonstrate the safety and efficacy of continuous ultrasound monitoring of the artery occlusion area (sonotrombotripsy) in patients with acute middle cerebral artery (MCA) occlusion. A total of 52concecutive patients with acute MCA occlusion were included in the thrombotripsy group. Doppler monitoring of the region of occlusion was performed for up to 45 min. The control group was created from the NAIS study database. Patients were matched for their vascular status, age, sex, artery occlusion, NIHSS at admission, rt-PA treatment and time to the first ultrasound examinations. The number of recanalized arteries at 6 and 24 h after the onset of symptoms, the number of independent patients (mRS 0-2 versus 3-6) after 90 d, and the number of serious adverse events were statistically evaluated. In the thrombotripsy group, 19 patients (36.5%) had complete recanalization and 27 (51.9%) patients had partial recanalization at 1 h after the start of the TCCS monitoring. Higher recan

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/NR9487" target="_blank" >NR9487: Aktivace fibrinolytického systému pomocí kontinuálního ultrazvukového monitoring u pacientů s ischemickou cévní mozkovu příhodou a dobrovolníků</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Ultrasound in Medicine and Biology

ISSN

0301-5629

e-ISSN

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Svazek periodika

34

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

1175-1782

Kód UT WoS článku

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EID výsledku v databázi Scopus

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