Risk reduction of brain infarction during carotid endarterectomy or stenting using sonolysis - prospective randomized study pilot data

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F12%3A00102840" target="_blank" >RIV/00843989:_____/12:00102840 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1063/1.4769951" target="_blank" >http://dx.doi.org/10.1063/1.4769951</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1063/1.4769951" target="_blank" >10.1063/1.4769951</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Risk reduction of brain infarction during carotid endarterectomy or stenting using sonolysis - prospective randomized study pilot data

Popis výsledku v původním jazyce

Sonolysis is a new therapeutic option for the acceleration of arterial recanalization. The aim of this study was to confirm risk reduction of brain infarction during endarterectomy (CEA) and stenting (CAS) of the internal carotid artery (ICA) using sonolysis with continuous transcranial Doppler (TCD) monitoring by diagnostic 2 MHz probe, additional interest was to assess impact of new brain ischemic lesions on cognitive functions. Methods: All consecutive patients 1/ with ICA stenosis >70%, 2/ indicatedto CEA or CAS, 3/ with signed informed consent, were enrolled to the prospective study during 17 months. Patients were randomized into 2 groups: Group 1 with sonolysis during intervention and Group 2 without sonolysis. Neurological examination, assessment of cognitive functions and brain magnetic resonance imaging (MRI) were performed before and 24 hours after intervention in all patients. Occurrence of new brain infarctions (including infarctions >0.5 cm3), and the results of Mini-Ment

Název v anglickém jazyce

Risk reduction of brain infarction during carotid endarterectomy or stenting using sonolysis - prospective randomized study pilot data

Popis výsledku anglicky

Sonolysis is a new therapeutic option for the acceleration of arterial recanalization. The aim of this study was to confirm risk reduction of brain infarction during endarterectomy (CEA) and stenting (CAS) of the internal carotid artery (ICA) using sonolysis with continuous transcranial Doppler (TCD) monitoring by diagnostic 2 MHz probe, additional interest was to assess impact of new brain ischemic lesions on cognitive functions. Methods: All consecutive patients 1/ with ICA stenosis >70%, 2/ indicatedto CEA or CAS, 3/ with signed informed consent, were enrolled to the prospective study during 17 months. Patients were randomized into 2 groups: Group 1 with sonolysis during intervention and Group 2 without sonolysis. Neurological examination, assessment of cognitive functions and brain magnetic resonance imaging (MRI) were performed before and 24 hours after intervention in all patients. Occurrence of new brain infarctions (including infarctions >0.5 cm3), and the results of Mini-Ment

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

—

Projekt

<a href="/cs/project/NT11386" target="_blank" >NT11386: Snížení rizika vzniku symptomatického a klinicky němého mozkového infarktu v průběhu karotické endarterektomie a karotického stentingu pomocí aktivace fibrinolytického systému kontinuálním transkraniálním dopplerovským monitoringem</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

AIP Conference Proceedings

ISSN

0094-243X

e-ISSN

—

Svazek periodika

1503

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

239-243

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—