Immunological and autoimmune considerations of Autism Spectrum Disorders

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F13%3AE0104040" target="_blank" >RIV/00843989:_____/13:E0104040 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jaut.2013.05.005" target="_blank" >http://dx.doi.org/10.1016/j.jaut.2013.05.005</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jaut.2013.05.005" target="_blank" >10.1016/j.jaut.2013.05.005</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Immunological and autoimmune considerations of Autism Spectrum Disorders

Popis výsledku v původním jazyce

Autism Spectrum Disorders (ASD) are a group of heterogeneous neurodevelopmental conditions presenting in early childhood with a prevalence ranging from 0.7% to 2.64%. Social interaction and communication skills are impaired and children often present with unusual repetitive behavior. The condition persists for life with major implications for the individual, the family and the entire health care system. While the etiology of ASD remains unknown, various clues suggest a possible association with alteredimmune responses and ASD. Inflammation in the brain and CNS has been reported by several groups with notable microglia activation and increased cytokine production in postmortem brain specimens of young and old individuals with ASD. Moreover several laboratories have isolated distinctive brain and CNS reactive antibodies from individuals with ASD. Large population based epidemiological studies have established a correlation between ASD and a family history of autoimmune diseases, associa

Název v anglickém jazyce

Immunological and autoimmune considerations of Autism Spectrum Disorders

Popis výsledku anglicky

Autism Spectrum Disorders (ASD) are a group of heterogeneous neurodevelopmental conditions presenting in early childhood with a prevalence ranging from 0.7% to 2.64%. Social interaction and communication skills are impaired and children often present with unusual repetitive behavior. The condition persists for life with major implications for the individual, the family and the entire health care system. While the etiology of ASD remains unknown, various clues suggest a possible association with alteredimmune responses and ASD. Inflammation in the brain and CNS has been reported by several groups with notable microglia activation and increased cytokine production in postmortem brain specimens of young and old individuals with ASD. Moreover several laboratories have isolated distinctive brain and CNS reactive antibodies from individuals with ASD. Large population based epidemiological studies have established a correlation between ASD and a family history of autoimmune diseases, associa

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of autoimmunity

ISSN

0896-8411

e-ISSN

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Svazek periodika

44

Číslo periodika v rámci svazku

n. August

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

"p. 1-7"

Kód UT WoS článku

000323691300001

EID výsledku v databázi Scopus

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