Anaerobic metabolism associated with traumatic hemorrhagic shock monitored by microdialysis of muscle tissue is dependent on the levels of hemoglobin and central venous oxygen saturation: a prospective, observational study
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F14%3AE0103900" target="_blank" >RIV/00843989:_____/14:E0103900 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61988987:17110/14:A1501CQ5
Výsledek na webu
<a href="http://dx.doi.org/10.1186/1757-7241-22-11" target="_blank" >http://dx.doi.org/10.1186/1757-7241-22-11</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/1757-7241-22-11" target="_blank" >10.1186/1757-7241-22-11</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Anaerobic metabolism associated with traumatic hemorrhagic shock monitored by microdialysis of muscle tissue is dependent on the levels of hemoglobin and central venous oxygen saturation: a prospective, observational study
Popis výsledku v původním jazyce
Background: Traumatic hemorrhagic shock resulting in tissue hypoxia is a significant cause of morbidity and mortality in polytraumatized patients. Early identification of tissue hypoxia is possible with microdialysis. The aim of this study was to determine the correlation between a marker of tissue hypoxia (L/P; lactate to pyruvate ratio) and selected parameters of systemic oxygen delivery (Hb; hemoglobin) and oxygen extraction (ScvO(2); central venous oxygen saturation). We also investigated the severity of tissue hypoxia over the course of care. Methods: Adult patients with traumatic hemorrhagic shock were enrolled in this prospective, observational study. Microdialysis of the peripheral muscle tissue was performed. Demographic data and timeline of care were collected. Tissue lactate, pyruvate, glycerol, glucose levels, hemoglobin, serum lactate and oxygen saturation of the central venous blood (ScvO(2)) levels were also measured. Results: The L/P ratio trend may react to changes in
Název v anglickém jazyce
Anaerobic metabolism associated with traumatic hemorrhagic shock monitored by microdialysis of muscle tissue is dependent on the levels of hemoglobin and central venous oxygen saturation: a prospective, observational study
Popis výsledku anglicky
Background: Traumatic hemorrhagic shock resulting in tissue hypoxia is a significant cause of morbidity and mortality in polytraumatized patients. Early identification of tissue hypoxia is possible with microdialysis. The aim of this study was to determine the correlation between a marker of tissue hypoxia (L/P; lactate to pyruvate ratio) and selected parameters of systemic oxygen delivery (Hb; hemoglobin) and oxygen extraction (ScvO(2); central venous oxygen saturation). We also investigated the severity of tissue hypoxia over the course of care. Methods: Adult patients with traumatic hemorrhagic shock were enrolled in this prospective, observational study. Microdialysis of the peripheral muscle tissue was performed. Demographic data and timeline of care were collected. Tissue lactate, pyruvate, glycerol, glucose levels, hemoglobin, serum lactate and oxygen saturation of the central venous blood (ScvO(2)) levels were also measured. Results: The L/P ratio trend may react to changes in
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FI - Traumatologie a ortopedie
OECD FORD obor
—
Návaznosti výsledku
Projekt
<a href="/cs/project/NT11371" target="_blank" >NT11371: Metabolická odezva organismu u polytraumat</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Scandinavian journal of trauma resuscitation & emergency medicine
ISSN
1757-7241
e-ISSN
—
Svazek periodika
22
Číslo periodika v rámci svazku
11
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
9
Strana od-do
"p. 1-9"
Kód UT WoS článku
000331720300001
EID výsledku v databázi Scopus
—