Identifying obstructive sleep apnea in at-risk youth: an exploratory cross-sectional study in adolescents living with obesity

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F25%3AE0112142" target="_blank" >RIV/00843989:_____/25:E0112142 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61988987:17110/25:A2603COV

Výsledek na webu

<a href="https://www.biomed.cas.cz/physiolres/pdf/74/74_S107.pdf" target="_blank" >https://www.biomed.cas.cz/physiolres/pdf/74/74_S107.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.33549/physiolres.935752" target="_blank" >10.33549/physiolres.935752</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Identifying obstructive sleep apnea in at-risk youth: an exploratory cross-sectional study in adolescents living with obesity

Popis výsledku v původním jazyce

Obstructive sleep apnea (OSA) is one of the most common sleep disorders, affecting 1-10 % of children. A key risk factor is elevated body mass index (BMI). This exploratory study aimed to assess OSA prevalence and severity in adolescents living with obesity and explore associations with clinical and metabolic parameters. Adolescents with obesity aged 10-15 years hospitalized for weight management were enrolled. Participants underwent examination including anthropometry, blood pressure, and lipid profile. BMI was evaluated using WHO BMI-for-age z-scores and an internal standard deviation score (SDS). Sleep-disordered breathing was assessed using cardiorespiratory polygraphy. OSA severity was classified by pediatric AASM criteria using the apnea-hypopnea index (AHI). Among 26 adolescents, OSA occurred in 25 (96.2 %). Median AHI was 9.6 (IQR 5.3-19.1); 44 % had severe, 40 % moderate, and 16 % mild OSA. Severe OSA was more frequently observed in boys (p=0.045), who also showed significantly higher BMI z-score, ODI3 and T90 values; (p<0.05). Adolescents with severe OSA had higher body weight and BMI z-scores; (p<0.05). In regression models using BMI SDS, male sex emerged as a borderline predictor of higher AHI (beta=9.07; p=0.051), while age and BMI metrics were not significant. Spearman analysis further revealed a moderate positive correlation between BMI z-score and T90 (rho=0.51, p=0.02). In this exploratory study, OSA was detected in the majority of adolescents living with obesity, though results should be interpreted with caution. Early recognition may support interventions to limit adverse outcomes. Larger polysomnographic studies with control groups are required to confirm prevalence and clarify risk factors.

Název v anglickém jazyce

Identifying obstructive sleep apnea in at-risk youth: an exploratory cross-sectional study in adolescents living with obesity

Popis výsledku anglicky

Obstructive sleep apnea (OSA) is one of the most common sleep disorders, affecting 1-10 % of children. A key risk factor is elevated body mass index (BMI). This exploratory study aimed to assess OSA prevalence and severity in adolescents living with obesity and explore associations with clinical and metabolic parameters. Adolescents with obesity aged 10-15 years hospitalized for weight management were enrolled. Participants underwent examination including anthropometry, blood pressure, and lipid profile. BMI was evaluated using WHO BMI-for-age z-scores and an internal standard deviation score (SDS). Sleep-disordered breathing was assessed using cardiorespiratory polygraphy. OSA severity was classified by pediatric AASM criteria using the apnea-hypopnea index (AHI). Among 26 adolescents, OSA occurred in 25 (96.2 %). Median AHI was 9.6 (IQR 5.3-19.1); 44 % had severe, 40 % moderate, and 16 % mild OSA. Severe OSA was more frequently observed in boys (p=0.045), who also showed significantly higher BMI z-score, ODI3 and T90 values; (p<0.05). Adolescents with severe OSA had higher body weight and BMI z-scores; (p<0.05). In regression models using BMI SDS, male sex emerged as a borderline predictor of higher AHI (beta=9.07; p=0.051), while age and BMI metrics were not significant. Spearman analysis further revealed a moderate positive correlation between BMI z-score and T90 (rho=0.51, p=0.02). In this exploratory study, OSA was detected in the majority of adolescents living with obesity, though results should be interpreted with caution. Early recognition may support interventions to limit adverse outcomes. Larger polysomnographic studies with control groups are required to confirm prevalence and clarify risk factors.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30209 - Paediatrics

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Physiological research

ISSN

0862-8408

e-ISSN

1802-9973

Svazek periodika

74

Číslo periodika v rámci svazku

suppl.1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

1

Strana od-do

s107-s116

Kód UT WoS článku

001690902000008

EID výsledku v databázi Scopus

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