Pseudohyperkalemia - Potassium released from cells due to clotting and centrifugation - a case report

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27661989%3A_____%2F18%3AN0000004" target="_blank" >RIV/27661989:_____/18:N0000004 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61988987:17110/18:A1901RS0

Výsledek na webu

<a href="https://www.biochemia-medica.com/en/journal/28/1/10.11613/BM.2018.011002" target="_blank" >https://www.biochemia-medica.com/en/journal/28/1/10.11613/BM.2018.011002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.11613/BM.2018.011002" target="_blank" >10.11613/BM.2018.011002</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Pseudohyperkalemia - Potassium released from cells due to clotting and centrifugation - a case report

Popis výsledku v původním jazyce

Hyperkalemia is a potentially lethal condition. Pseudohyperkalemia should be always excluded before implementing treatment to prevent inappropriate cause of hypokalemia - equally a potentially lethal condition. Here we present a case report of a 62 year female with chronic myeloproliferative disorder, i.e. essential thrombocythemia. The laboratory test results for potassium concentration were 6.3 mmol/L, for platelet count 1305 x 10(9)/L and for leukocyte count 39.8 x 10(9)/L. This was due to a temporary drug withdrawal after a surgical intervention for gastric bleeding. Potassium concentration in lithium heparin plasma collected in a vacuum tube without gel separator and in whole blood syringe were 4.6 mmol/L and 3.4 mmol/L, respectively. It means that mechanical stress such as centrifugation can contribute to spurious hyperkalemia. Prior to reporting unexpected hyperkalemia result, pseudohyperkalemia should always be considered by the laboratory. Such potassium results require investigation in case it is pseudohyperkalemia, which may be due to thrombocytosis and leukocytosis. In cases where thrombocytosis or leukocytosis exists, an interpretative comment indicating these conditions inserted with the results of the potassium concentration can increase awareness for more accurate patient care decisions.

Název v anglickém jazyce

Pseudohyperkalemia - Potassium released from cells due to clotting and centrifugation - a case report

Popis výsledku anglicky

Hyperkalemia is a potentially lethal condition. Pseudohyperkalemia should be always excluded before implementing treatment to prevent inappropriate cause of hypokalemia - equally a potentially lethal condition. Here we present a case report of a 62 year female with chronic myeloproliferative disorder, i.e. essential thrombocythemia. The laboratory test results for potassium concentration were 6.3 mmol/L, for platelet count 1305 x 10(9)/L and for leukocyte count 39.8 x 10(9)/L. This was due to a temporary drug withdrawal after a surgical intervention for gastric bleeding. Potassium concentration in lithium heparin plasma collected in a vacuum tube without gel separator and in whole blood syringe were 4.6 mmol/L and 3.4 mmol/L, respectively. It means that mechanical stress such as centrifugation can contribute to spurious hyperkalemia. Prior to reporting unexpected hyperkalemia result, pseudohyperkalemia should always be considered by the laboratory. Such potassium results require investigation in case it is pseudohyperkalemia, which may be due to thrombocytosis and leukocytosis. In cases where thrombocytosis or leukocytosis exists, an interpretative comment indicating these conditions inserted with the results of the potassium concentration can increase awareness for more accurate patient care decisions.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30200 - Clinical medicine

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biochemia Medica

ISSN

1330-0962

e-ISSN

1846-7482

Svazek periodika

28

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

HR - Chorvatská republika

Počet stran výsledku

5

Strana od-do

011002

Kód UT WoS článku

000425617200019

EID výsledku v databázi Scopus

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