Calcium Kidney Stone Patient with Normocalcemia

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27661989%3A_____%2F24%3A10003344" target="_blank" >RIV/27661989:_____/24:10003344 - isvavai.cz</a>

Výsledek na webu

<a href="https://academic.oup.com/jalm/article/9/3/641/7613052" target="_blank" >https://academic.oup.com/jalm/article/9/3/641/7613052</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/jalm/jfad135" target="_blank" >10.1093/jalm/jfad135</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Calcium Kidney Stone Patient with Normocalcemia

Popis výsledku v původním jazyce

This case report presents an 18-year-old female patient with recurrent calcium kidney stones and normocalcemia masking primary hyperparathyroidism. Initial laboratory evaluation revealed vitamin D deficiency, hypomagnesuria, mild hypercalciuria, and elevated parathyroid hormone (PTH), supporting a diagnosis of secondary hyperparathyroidism. Following vitamin D supplementation, persistent PTH elevation together with the development of hypercalcemia uncovered an underlying parathyroid adenoma, which was surgically removed, leading to normalization of biochemical parameters. The case emphasizes the essential role of 25-OH vitamin D measurement in the differential diagnosis of calcium nephrolithiasis and demonstrates that combined primary and secondary hyperparathyroidism may clinically present as normocalcemic stone disease.

Název v anglickém jazyce

Calcium Kidney Stone Patient with Normocalcemia

Popis výsledku anglicky

This case report presents an 18-year-old female patient with recurrent calcium kidney stones and normocalcemia masking primary hyperparathyroidism. Initial laboratory evaluation revealed vitamin D deficiency, hypomagnesuria, mild hypercalciuria, and elevated parathyroid hormone (PTH), supporting a diagnosis of secondary hyperparathyroidism. Following vitamin D supplementation, persistent PTH elevation together with the development of hypercalcemia uncovered an underlying parathyroid adenoma, which was surgically removed, leading to normalization of biochemical parameters. The case emphasizes the essential role of 25-OH vitamin D measurement in the differential diagnosis of calcium nephrolithiasis and demonstrates that combined primary and secondary hyperparathyroidism may clinically present as normocalcemic stone disease.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Applied Laboratory Medicine

ISSN

2576-9456

e-ISSN

2475-7241

Svazek periodika

9

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

4

Strana od-do

641-644

Kód UT WoS článku

001174399200001

EID výsledku v databázi Scopus

—