Study of possible separation of phenylacetic acid from fermentation broth by electrodialysis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F28676092%3A_____%2F18%3AN0000057" target="_blank" >RIV/28676092:_____/18:N0000057 - isvavai.cz</a>

Výsledek na webu

<a href="http://sschi.chtf.stuba.sk/ssche_conference2019.html" target="_blank" >http://sschi.chtf.stuba.sk/ssche_conference2019.html</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Study of possible separation of phenylacetic acid from fermentation broth by electrodialysis

Popis výsledku v původním jazyce

Biologically produced chemicals are widely used in pharmaceutical and cosmetics industry. However, the drawback of biologically produced organic acids and other compounds is their downstream processing. Downstream processing of biochemical products requires recovery of one particular compound from a complex mixture. The downstream concentration and purification is an integral part of production process and significantly contributes to production costs. Downstream processing costs can create up to 90 % of total production costs. Phenylacetic acid (PAA) is a useful compound in pharmaceutical and cosmetics industry. In pharmaceutical industry it is, for example, used for production of penicillin G and diclofenac. In cosmetics industry is phenylacetic acid valuable chemical thanks to its honey-like odor. Goal of this work was to study if it is possible to separate phenylacetic acid from fermentation broth and subsequently purify it by conventional electrodialysis. Phenylacetic acid can form a monovalent anion at alkaline pH (pKa of PAA is 4.31), therefore it is possible to use electrodialysis for its removal from other uncharged compounds.

Název v anglickém jazyce

Study of possible separation of phenylacetic acid from fermentation broth by electrodialysis

Popis výsledku anglicky

Biologically produced chemicals are widely used in pharmaceutical and cosmetics industry. However, the drawback of biologically produced organic acids and other compounds is their downstream processing. Downstream processing of biochemical products requires recovery of one particular compound from a complex mixture. The downstream concentration and purification is an integral part of production process and significantly contributes to production costs. Downstream processing costs can create up to 90 % of total production costs. Phenylacetic acid (PAA) is a useful compound in pharmaceutical and cosmetics industry. In pharmaceutical industry it is, for example, used for production of penicillin G and diclofenac. In cosmetics industry is phenylacetic acid valuable chemical thanks to its honey-like odor. Goal of this work was to study if it is possible to separate phenylacetic acid from fermentation broth and subsequently purify it by conventional electrodialysis. Phenylacetic acid can form a monovalent anion at alkaline pH (pKa of PAA is 4.31), therefore it is possible to use electrodialysis for its removal from other uncharged compounds.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

20402 - Chemical process engineering

Projekt

<a href="/cs/project/LO1418" target="_blank" >LO1418: Progresivní rozvoj Membránového inovačního centra</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

PROCEEDINGS - 45th International Conference of Slovak Society of Chemical Engineering

ISBN

978-80-89597-89-5

ISSN

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e-ISSN

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Počet stran výsledku

2

Strana od-do

124-125

Název nakladatele

Slovak Society of Chemical Engineering

Místo vydání

Bratislava

Místo konání akce

Tatranské Matliare

Datum konání akce

21. 5. 2018

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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