Microscopy of material surfaces for tissue engineering

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13440%2F16%3A43888346" target="_blank" >RIV/44555601:13440/16:43888346 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22310/16:43902514

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Microscopy of material surfaces for tissue engineering

Popis výsledku v původním jazyce

The field of material surface modification with aim of biomaterials construction involves several approaches based on surface treatments that allow to prepare materials, which support the cell adhesion and proliferation and thus aid and improve the tissue formation. Modified materials have a surface composition and morphology intended to interact with biological systems and cellular functions. Not only surface chemistry has an effect on material biological response, surface structures of different morphology can be constructed to guide a desirable biological outcome. Nano-patterned material surfaces have been tested with aim to determine how surface geometry, physical and chemical properties on a micro- and nano-scale can affect cellular response and influence cell adhesion and proliferation. Surface physico-chemical properties (e.g. chemistry, morphology, wettability, electrical conductivity, optical and mechanical properties) of treated surfaces were determined. The enhancement in cell adhesion and proliferation on modified substrates was studied in vitro. Bactericidal action of noble metal nano-particles (e.g. Au, Ag) on polymers was characterized. The influence of metal nano-particles grafting by using metal nano-particle suspension prepared by "green" methods was determined.

Název v anglickém jazyce

Microscopy of material surfaces for tissue engineering

Popis výsledku anglicky

The field of material surface modification with aim of biomaterials construction involves several approaches based on surface treatments that allow to prepare materials, which support the cell adhesion and proliferation and thus aid and improve the tissue formation. Modified materials have a surface composition and morphology intended to interact with biological systems and cellular functions. Not only surface chemistry has an effect on material biological response, surface structures of different morphology can be constructed to guide a desirable biological outcome. Nano-patterned material surfaces have been tested with aim to determine how surface geometry, physical and chemical properties on a micro- and nano-scale can affect cellular response and influence cell adhesion and proliferation. Surface physico-chemical properties (e.g. chemistry, morphology, wettability, electrical conductivity, optical and mechanical properties) of treated surfaces were determined. The enhancement in cell adhesion and proliferation on modified substrates was studied in vitro. Bactericidal action of noble metal nano-particles (e.g. Au, Ag) on polymers was characterized. The influence of metal nano-particles grafting by using metal nano-particle suspension prepared by "green" methods was determined.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

JJ - Ostatní materiály

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Manufacturing Technology

ISSN

1213-2489

e-ISSN

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Svazek periodika

16

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

1162-1168

Kód UT WoS článku

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EID výsledku v databázi Scopus

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