Neuron adhesion on diamond: competition between polymer treatment and surface morphology

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F18%3A00494905" target="_blank" >RIV/68378271:_____/18:00494905 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68407700:21460/18:00339421

Výsledek na webu

<a href="http://dx.doi.org/10.1002/adem.201800182" target="_blank" >http://dx.doi.org/10.1002/adem.201800182</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/adem.201800182" target="_blank" >10.1002/adem.201800182</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Neuron adhesion on diamond: competition between polymer treatment and surface morphology

Popis výsledku v původním jazyce

The ability to form an efficient interface between material and neural cells is a crucial aspect for construction of neuroelectrodes. Diamond offers material characteristics that could, to a large extent, improve the performance of neuroelectrodes. The greatest advantage of diamond is a large variety of material and surface properties such as electrical conductivity, surface morphology, and surface chemistry. Such a variety of material characteristics can lead to various cellular responses. Here, the authors compare survival, adhesion, and neurite formation of primary neurons on diamond thin films of various morphologies and treatments with several types of polymers commonly used to enhance cell adhesion. The authors find that the variation of surface roughness of nanocrystalline diamond film when coated with polymer does not have a major influence on neuron survival or adhesion. The adhesion of neurons can be influenced by the selected type of polymer coating.

Název v anglickém jazyce

Neuron adhesion on diamond: competition between polymer treatment and surface morphology

Popis výsledku anglicky

The ability to form an efficient interface between material and neural cells is a crucial aspect for construction of neuroelectrodes. Diamond offers material characteristics that could, to a large extent, improve the performance of neuroelectrodes. The greatest advantage of diamond is a large variety of material and surface properties such as electrical conductivity, surface morphology, and surface chemistry. Such a variety of material characteristics can lead to various cellular responses. Here, the authors compare survival, adhesion, and neurite formation of primary neurons on diamond thin films of various morphologies and treatments with several types of polymers commonly used to enhance cell adhesion. The authors find that the variation of surface roughness of nanocrystalline diamond film when coated with polymer does not have a major influence on neuron survival or adhesion. The adhesion of neurons can be influenced by the selected type of polymer coating.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10302 - Condensed matter physics (including formerly solid state physics, supercond.)

Projekt

<a href="/cs/project/GA17-15319S" target="_blank" >GA17-15319S: Diamantová mikroelektrodová pole pro duální monitorování nervových signálů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Advanced Engineering Materials

ISSN

1438-1656

e-ISSN

—

Svazek periodika

20

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

10

Strana od-do

—

Kód UT WoS článku

000445327200023

EID výsledku v databázi Scopus

2-s2.0-85053859063