Study of Biocompability of Modified Polyethylene

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Study of Biocompability of Modified Polyethylene

Popis výsledku v původním jazyce

Polyethylene (PE) is a synthetic polymer used for biomedical applications and tissue engineering. Surface modification of this material relates to changes of its surface hydrophilicity, chemistry, morphology, microstructure, roughness, and topography, all influencing its biological response. This our research was focused on modification of PE by argon plasma discharge and then grafting with biologically active polyethylene glycol (PEG) with the aim to enhance its cytocompatibility of the cell lines L929 of mouse fibroblast. The surface properties of pristine PE and its grafted counterparts were studied by different experimental techniques: X-ray spectroscopy, goniometry, Atomic Force Microscopy and electrokinetic analysis (zeta potential). Our results show that grafting of PEG leads to higher wettability, surface roughness, and thus the adhesion and proliferation of cultured cells.

Název v anglickém jazyce

Study of Biocompability of Modified Polyethylene

Popis výsledku anglicky

Polyethylene (PE) is a synthetic polymer used for biomedical applications and tissue engineering. Surface modification of this material relates to changes of its surface hydrophilicity, chemistry, morphology, microstructure, roughness, and topography, all influencing its biological response. This our research was focused on modification of PE by argon plasma discharge and then grafting with biologically active polyethylene glycol (PEG) with the aim to enhance its cytocompatibility of the cell lines L929 of mouse fibroblast. The surface properties of pristine PE and its grafted counterparts were studied by different experimental techniques: X-ray spectroscopy, goniometry, Atomic Force Microscopy and electrokinetic analysis (zeta potential). Our results show that grafting of PEG leads to higher wettability, surface roughness, and thus the adhesion and proliferation of cultured cells.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

20501 - Materials engineering

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

8TH INTERNATIONAL CONFERENCE ON NANOMATERIALS - RESEARCH &amp; APPLICATION (NANOCON 2016)

ISBN

978-80-87294-71-0

ISSN

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e-ISSN

neuvedeno

Počet stran výsledku

6

Strana od-do

572-577

Název nakladatele

TANGER Ltd; Reg Ctr Adv Technologies &amp; Mat; Czech Soc New Mat &amp; Technologies

Místo vydání

Brno

Místo konání akce

Brno

Datum konání akce

19. 10. 2016

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000410656100100