Nanofiber Tubes as Vascular Grafts

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F12%3A%230001150" target="_blank" >RIV/46747885:24410/12:#0001150 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Nanofiber Tubes as Vascular Grafts

Popis výsledku v původním jazyce

Tubes as vascular grafts made of polymeric nanofibers are very promising technology in the field of tissue engineering. A tube produced by an electrospinning technology consists of 2 layers. The choice of polymers plays an important role for electrospinning and can improve many different requests. The first layer was made from polycaprolactone (PCL) to ensure mechanical properties and the second layer was electrospun from pure chitosan (CS) which could improve the cytocompatibility of the tube for vascular tissue engineering. Vacular scaffolds fabricated by electrospinning of synthetic and natural polymers have been designed to provide adequate mechanical support as well as favorable adhesion substrate for vascular cells. PCL is frequently used vascular scaffold biomaterial because of its mechanical strength and ease of fabrication but also lacks blood and cellular biocompatibility because of its hydrophobicity. Natural polymers improve the cytocompatibility of the scaffold. The morpoh

Název v anglickém jazyce

Nanofiber Tubes as Vascular Grafts

Popis výsledku anglicky

Tubes as vascular grafts made of polymeric nanofibers are very promising technology in the field of tissue engineering. A tube produced by an electrospinning technology consists of 2 layers. The choice of polymers plays an important role for electrospinning and can improve many different requests. The first layer was made from polycaprolactone (PCL) to ensure mechanical properties and the second layer was electrospun from pure chitosan (CS) which could improve the cytocompatibility of the tube for vascular tissue engineering. Vacular scaffolds fabricated by electrospinning of synthetic and natural polymers have been designed to provide adequate mechanical support as well as favorable adhesion substrate for vascular cells. PCL is frequently used vascular scaffold biomaterial because of its mechanical strength and ease of fabrication but also lacks blood and cellular biocompatibility because of its hydrophobicity. Natural polymers improve the cytocompatibility of the scaffold. The morpoh

Druh

O - Ostatní výsledky

CEP obor

FJ - Chirurgie včetně transplantologie

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů