Assessment of cell adhesion on electrospun polycaprolactone scaffold sterilized by ethylene oxide

Kód výsledku v IS VaVaI

RIV/46747885:24410/17:00004182 - isvavai.cz

Výsledek na webu

http://www.esb2017.org/

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Assessment of cell adhesion on electrospun polycaprolactone scaffold sterilized by ethylene oxide

Popis výsledku v původním jazyce

Nanofibrous scaffolds are promising materials for construction of tissue engineering scaffolds due to their similar morphology with extracellular matrix. Polycaprolactone is a synthetic polymer commonly used for various applications due to its cytocompatibility and biodegradability. Terminal sterilization of electrospun polycaprolactone nanofibers could significantly change properties of the scaffold therefore the impact of ethylene oxide sterilization was studied in vitro in presented work. The results showed lowered adhesion of cell lines compared to ethanol sterilized materials.

Název v anglickém jazyce

Assessment of cell adhesion on electrospun polycaprolactone scaffold sterilized by ethylene oxide

Popis výsledku anglicky

Nanofibrous scaffolds are promising materials for construction of tissue engineering scaffolds due to their similar morphology with extracellular matrix. Polycaprolactone is a synthetic polymer commonly used for various applications due to its cytocompatibility and biodegradability. Terminal sterilization of electrospun polycaprolactone nanofibers could significantly change properties of the scaffold therefore the impact of ethylene oxide sterilization was studied in vitro in presented work. The results showed lowered adhesion of cell lines compared to ethanol sterilized materials.

Druh

O - Ostatní výsledky

CEP obor

—

OECD FORD obor

21001 - Nano-materials (production and properties)

Projekt

NV15-29241A: Nanovlákenná biodegradabilní maloprůměrová cévní náhrada

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů