The effect of ethylene oxide sterilization on electrospun vascular grafts made from biodegradable polyesters

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F18%3A00005477" target="_blank" >RIV/46747885:24410/18:00005477 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985891:_____/18:00497258 RIV/46747885:24620/18:00005477

Výsledek na webu

<a href="https://api.elsevier.com/content/article/eid/1-s2.0-S0928493117338821" target="_blank" >https://api.elsevier.com/content/article/eid/1-s2.0-S0928493117338821</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.msec.2018.06.041" target="_blank" >10.1016/j.msec.2018.06.041</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The effect of ethylene oxide sterilization on electrospun vascular grafts made from biodegradable polyesters

Popis výsledku v původním jazyce

The study describes the detailed examination of the effect of ethylene oxide sterilization on electrospun scaffolds constructed from biodegradable polyesters. Different fibrous layers fabricated from polycaprolactone (PCL) and a copolymer consisting of polylactide and polycaprolactone (PLCL) were investigated for the determination of their mechanical properties, degradation rates and interaction with fibroblasts. It was discovered that the sterilization procedure influenced the mechanical properties of the electrospun PLCL copolymer scaffold to the greatest extent. No effect of ethylene oxide sterilization on degradation behavior was observed. However, a delayed fibroblast proliferation rate was noticed with concern to the ethylene oxide sterilized samples compared to the ethanol sterilization of the materials.

Název v anglickém jazyce

The effect of ethylene oxide sterilization on electrospun vascular grafts made from biodegradable polyesters

Popis výsledku anglicky

The study describes the detailed examination of the effect of ethylene oxide sterilization on electrospun scaffolds constructed from biodegradable polyesters. Different fibrous layers fabricated from polycaprolactone (PCL) and a copolymer consisting of polylactide and polycaprolactone (PLCL) were investigated for the determination of their mechanical properties, degradation rates and interaction with fibroblasts. It was discovered that the sterilization procedure influenced the mechanical properties of the electrospun PLCL copolymer scaffold to the greatest extent. No effect of ethylene oxide sterilization on degradation behavior was observed. However, a delayed fibroblast proliferation rate was noticed with concern to the ethylene oxide sterilized samples compared to the ethanol sterilization of the materials.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Materials Science and Engineering C

ISSN

0928-4931

e-ISSN

—

Svazek periodika

92

Číslo periodika v rámci svazku

NOV

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

11

Strana od-do

132-142

Kód UT WoS článku

000445309700015

EID výsledku v databázi Scopus

2-s2.0-85049039502