Composite scaffold for bone tissue engineering

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F18%3A00006055" target="_blank" >RIV/46747885:24410/18:00006055 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Composite scaffold for bone tissue engineering

Popis výsledku v původním jazyce

The work is focused on preparation of biological composite scaffold for bone regeneration. The scaffold consisted of a calcium phosphate grid, the grid was printed using the Prusa printer. The printed grid was subsequently coated with polycaprolactone nanofibres containing hydroxyapatite particles. The individual components, and the entire composite scaffolds, were in-vitro tested with human cell line MG-63. During the experiment, testing of the nanofibrous layer of polycaprolactone without hydroxyapatite particles was performed, and testing resulted in higher cell viability in samples containing hydroxyapatite particles. The final composite scaffold has demonstrated suitability for bone regenerative medicine and for use in further experiments, such as a combination with collagen hydrogel to promote cell viability.

Název v anglickém jazyce

Composite scaffold for bone tissue engineering

Popis výsledku anglicky

The work is focused on preparation of biological composite scaffold for bone regeneration. The scaffold consisted of a calcium phosphate grid, the grid was printed using the Prusa printer. The printed grid was subsequently coated with polycaprolactone nanofibres containing hydroxyapatite particles. The individual components, and the entire composite scaffolds, were in-vitro tested with human cell line MG-63. During the experiment, testing of the nanofibrous layer of polycaprolactone without hydroxyapatite particles was performed, and testing resulted in higher cell viability in samples containing hydroxyapatite particles. The final composite scaffold has demonstrated suitability for bone regenerative medicine and for use in further experiments, such as a combination with collagen hydrogel to promote cell viability.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Projekt

<a href="/cs/project/FV10416" target="_blank" >FV10416: Nanovlákenné kryty kožních defektů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů