INFLUENCE OF STERILIZATION METHODS ON NANOFIBROUS LAYERS MADE FROM PVDF

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F24%3A00012691" target="_blank" >RIV/46747885:24410/24:00012691 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.37904/nanocon.2023.4800" target="_blank" >https://doi.org/10.37904/nanocon.2023.4800</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.37904/nanocon.2023.4800" target="_blank" >10.37904/nanocon.2023.4800</a>

Jazyk výsledku

angličtina

Název v původním jazyce

INFLUENCE OF STERILIZATION METHODS ON NANOFIBROUS LAYERS MADE FROM PVDF

Popis výsledku v původním jazyce

Polyvinylidenefluoride (PVDF) is a biocompatible, nondegradable material commonly used in medicine as a surgical suture. However, the use of PVDF in the field of tissue engineering has more significant potential. One is the possibility of using nanofibrous PVDF layers for applications such as hernia meshes, glaucoma drainage implants, or nondegradable vascular grafts and verifying many properties, such as sterilization, precedes using such biomaterial in clinical practice. An inappropriately chosen method tends to disrupt the fibrous structure or affect the behavior of cells in contact with the material. Current literature does not provide a comparison of different sterilization methods on PVDF. The study is devoted to the influence of the most commonly used sterilization and disinfection methods on the nanofibrous PVDF layer prepared by the needleless electrospinning technique. Changes in fiber morphology, molecular weight, macroscopic changes, and behavior of cells on the material surface were monitored. It was discovered that the chosen methods do not affect fiber morphology or changes in molecular weight. However, the behavior of the cells on the materials sterilized by plasma was different.

Název v anglickém jazyce

INFLUENCE OF STERILIZATION METHODS ON NANOFIBROUS LAYERS MADE FROM PVDF

Popis výsledku anglicky

Polyvinylidenefluoride (PVDF) is a biocompatible, nondegradable material commonly used in medicine as a surgical suture. However, the use of PVDF in the field of tissue engineering has more significant potential. One is the possibility of using nanofibrous PVDF layers for applications such as hernia meshes, glaucoma drainage implants, or nondegradable vascular grafts and verifying many properties, such as sterilization, precedes using such biomaterial in clinical practice. An inappropriately chosen method tends to disrupt the fibrous structure or affect the behavior of cells in contact with the material. Current literature does not provide a comparison of different sterilization methods on PVDF. The study is devoted to the influence of the most commonly used sterilization and disinfection methods on the nanofibrous PVDF layer prepared by the needleless electrospinning technique. Changes in fiber morphology, molecular weight, macroscopic changes, and behavior of cells on the material surface were monitored. It was discovered that the chosen methods do not affect fiber morphology or changes in molecular weight. However, the behavior of the cells on the materials sterilized by plasma was different.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

21001 - Nano-materials (production and properties)

Projekt

<a href="/cs/project/NU23-08-00586" target="_blank" >NU23-08-00586: Antifibrotizační vlákenný materiál pro snižování nitroočního tlaku při glaukomovém onemocnění</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

NANOCON Conference Proceedings - International Conference on Nanomaterials

ISBN

978-80-88365-15-0

ISSN

2694-930X

e-ISSN

—

Počet stran výsledku

6

Strana od-do

313-318

Název nakladatele

TANGER Ltd.

Místo vydání

—

Místo konání akce

Brno

Datum konání akce

1. 1. 2023

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

001234125400050