Immobilization of Esterase Enzyme Onto Silica Nanofibers for Biomedical Applications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24620%2F14%3A%230000567" target="_blank" >RIV/46747885:24620/14:#0000567 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Immobilization of Esterase Enzyme Onto Silica Nanofibers for Biomedical Applications

Popis výsledku v původním jazyce

The search for new solutions to medical problems has led to a considerable development in the application of nanotechnologies to medicine. Silanization of substrates with hydroxyl (?OH), amino (?NH2) or carboxy (?COOH) functional groups on the surface ofnanofibers is a process currently being used in the engineering of biocompatible nanomaterials applicable to different types of wounds. This paper describes a successful procedure for immobilization of the esterase enzyme onto the surface of silica nanofibers through the silanization of surfaces with 3-aminopropyl triethoxysilane (APTES). The immobilized enzyme was detected by electron microscopy (SEM), atomic force microscopy (AFM), optical microscopy and specific histochemical reactions. The above-mentioned biomolecules were selected as a models for immobilisation another different types of enzymes, particuraly proteolytic enzymes.

Název v anglickém jazyce

Immobilization of Esterase Enzyme Onto Silica Nanofibers for Biomedical Applications

Popis výsledku anglicky

The search for new solutions to medical problems has led to a considerable development in the application of nanotechnologies to medicine. Silanization of substrates with hydroxyl (?OH), amino (?NH2) or carboxy (?COOH) functional groups on the surface ofnanofibers is a process currently being used in the engineering of biocompatible nanomaterials applicable to different types of wounds. This paper describes a successful procedure for immobilization of the esterase enzyme onto the surface of silica nanofibers through the silanization of surfaces with 3-aminopropyl triethoxysilane (APTES). The immobilized enzyme was detected by electron microscopy (SEM), atomic force microscopy (AFM), optical microscopy and specific histochemical reactions. The above-mentioned biomolecules were selected as a models for immobilisation another different types of enzymes, particuraly proteolytic enzymes.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

<a href="/cs/project/ED3.1.00%2F14.0295" target="_blank" >ED3.1.00/14.0295: Aplikace nanomateriálů a progresivních technologií</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Fibres and textiles (Vlákna a textil)

ISSN

1335-0617

e-ISSN

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Svazek periodika

21

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

9

Strana od-do

3-11

Kód UT WoS článku

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EID výsledku v databázi Scopus

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