Synthesis of cyclodextrin-pyrrole conjugates possessing tuneable carbon linkers

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24620%2F18%3A00005612" target="_blank" >RIV/46747885:24620/18:00005612 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/article/10.1007/s10847-018-0854-5" target="_blank" >https://link.springer.com/article/10.1007/s10847-018-0854-5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10847-018-0854-5" target="_blank" >10.1007/s10847-018-0854-5</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Synthesis of cyclodextrin-pyrrole conjugates possessing tuneable carbon linkers

Popis výsledku v původním jazyce

Cyclodextrins are naturally occurring cyclic oligosaccharides consisting of glucose units. The main feature of cyclodextrins is the ability to accommodate various lipophilic compounds in their interior, which determines them to be popular helpers to the mankind. However, there is still a demand for new derivatives for advanced applications. Herein, we report the synthesis of β-cyclodextrin–pyrrole conjugates. Their preparation is based on an amide bond formation or copper(I)-catalysed azide-alkyne cycloaddition between β-cyclodextrin and pyrrole derivatives. The main advantage of the synthetic approach lies in the possibility to attach the substituent in β-position, because polypyrroles possessing a substituent in this position are generally more conductive than the N-substituted ones. Moreover, the presented synthetic route is general and allows tuning the properties (various types of connections and lengths) of a linker. The presented cyclodextrin–pyrrole derivatives thus open the door for new applications in the field of sensors or tissue engineering.

Název v anglickém jazyce

Synthesis of cyclodextrin-pyrrole conjugates possessing tuneable carbon linkers

Popis výsledku anglicky

Cyclodextrins are naturally occurring cyclic oligosaccharides consisting of glucose units. The main feature of cyclodextrins is the ability to accommodate various lipophilic compounds in their interior, which determines them to be popular helpers to the mankind. However, there is still a demand for new derivatives for advanced applications. Herein, we report the synthesis of β-cyclodextrin–pyrrole conjugates. Their preparation is based on an amide bond formation or copper(I)-catalysed azide-alkyne cycloaddition between β-cyclodextrin and pyrrole derivatives. The main advantage of the synthetic approach lies in the possibility to attach the substituent in β-position, because polypyrroles possessing a substituent in this position are generally more conductive than the N-substituted ones. Moreover, the presented synthetic route is general and allows tuning the properties (various types of connections and lengths) of a linker. The presented cyclodextrin–pyrrole derivatives thus open the door for new applications in the field of sensors or tissue engineering.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10401 - Organic chemistry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Inclusion Phenomena and Macrocyclic Chemistry

ISSN

1388-3127

e-ISSN

—

Svazek periodika

92

Číslo periodika v rámci svazku

3-4

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

8

Strana od-do

339-346

Kód UT WoS článku

000451049300010

EID výsledku v databázi Scopus

2-s2.0-85056998295