Silver-shielded silica nanoparticles: Antimicrobial activity and biocompatibility primary evaluation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24620%2F18%3A00005687" target="_blank" >RIV/46747885:24620/18:00005687 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Silver-shielded silica nanoparticles: Antimicrobial activity and biocompatibility primary evaluation

Popis výsledku v původním jazyce

Antibacterial nanoparticles have been used and tested over last years due to their unique properties and excessive need for bacteriostatic products in medical care, food industry, clothing etc. Silver nanoparticles, leading group of these nanoparticles in terms of production, were proven to poses not only bacteriostatic but bactericidal character, and also have shown number of negative biological effects and cytotoxicity. Such reasons have been driving power to search for alternative concepts. One of the proposed ways to overcome the negative effects of silver NPs might be composite production combining their antibacterial nature with a convenient biocompatible material. In this study, possibilities of such core-shell nanoparticles were explored. Silver-shielded silica nanoparticles were produced by two-step chemical synthesis, characterized and their antimicrobial activity and biocompatibility were compared to commercial silver NPs (<100nm) used as a standard.

Název v anglickém jazyce

Silver-shielded silica nanoparticles: Antimicrobial activity and biocompatibility primary evaluation

Popis výsledku anglicky

Antibacterial nanoparticles have been used and tested over last years due to their unique properties and excessive need for bacteriostatic products in medical care, food industry, clothing etc. Silver nanoparticles, leading group of these nanoparticles in terms of production, were proven to poses not only bacteriostatic but bactericidal character, and also have shown number of negative biological effects and cytotoxicity. Such reasons have been driving power to search for alternative concepts. One of the proposed ways to overcome the negative effects of silver NPs might be composite production combining their antibacterial nature with a convenient biocompatible material. In this study, possibilities of such core-shell nanoparticles were explored. Silver-shielded silica nanoparticles were produced by two-step chemical synthesis, characterized and their antimicrobial activity and biocompatibility were compared to commercial silver NPs (<100nm) used as a standard.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

21001 - Nano-materials (production and properties)

Projekt

<a href="/cs/project/EF16_019%2F0000843" target="_blank" >EF16_019/0000843: Hybridní materiály pro hierarchické struktury</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů