Bactosim - the bacterial simulator

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F47813059%3A19240%2F13%3A%230004808" target="_blank" >RIV/47813059:19240/13:#0004808 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.slu.cz/su/slu/cz/projekty/webs/it4i" target="_blank" >http://www.slu.cz/su/slu/cz/projekty/webs/it4i</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Bactosim - the bacterial simulator

Popis výsledku v původním jazyce

The purpose of the conjugative simulator is to simulate the behavior of conjugation-based computing experiments within bacteria E. Coli. These experiments are based on interplay of three types of plasmids: pA, pB and pC. We use two strains of E. Coli: the producer strains which carry either the plasmid pA or pB, and the computing strain which originally carries the plasmid pC. Producer cells may contain different alleles of pA or pB. These plasmids are transferred to computing cells via the process of horizontal gene transfer so that most of the cells would end up containing three plasmids pA, pB and pC. The computing strain also contains a biochemical device called comparator. Its purpose is to evaluate whether the combination of alleles of pA and pBtogether with pC present in the cell satisfies certain pre-defined condition. In the negative case the comparator produces protein TetR which makes the plasmids pA and pB unstable. They are eventually lost and replaced by different allele

Název v anglickém jazyce

Bactosim - the bacterial simulator

Popis výsledku anglicky

The purpose of the conjugative simulator is to simulate the behavior of conjugation-based computing experiments within bacteria E. Coli. These experiments are based on interplay of three types of plasmids: pA, pB and pC. We use two strains of E. Coli: the producer strains which carry either the plasmid pA or pB, and the computing strain which originally carries the plasmid pC. Producer cells may contain different alleles of pA or pB. These plasmids are transferred to computing cells via the process of horizontal gene transfer so that most of the cells would end up containing three plasmids pA, pB and pC. The computing strain also contains a biochemical device called comparator. Its purpose is to evaluate whether the combination of alleles of pA and pBtogether with pC present in the cell satisfies certain pre-defined condition. In the negative case the comparator produces protein TetR which makes the plasmids pA and pB unstable. They are eventually lost and replaced by different allele

Druh

R - Software

CEP obor

IN - Informatika

OECD FORD obor

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Projekt

<a href="/cs/project/ED1.1.00%2F02.0070" target="_blank" >ED1.1.00/02.0070: Centrum excelence IT4Innovations</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Interní identifikační kód produktu

Bactosim

Technické parametry

Simulace kolonie o velikosti až 1 mil. bakterií

Ekonomické parametry

Volně šiřitelný software s licencí GNU GPL

IČO vlastníka výsledku

47813059

Název vlastníka

Slezská univerzita v Opavě