Two-scale modeling of tissue perfusion problem using homogenization of dual porous media

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F10%3A00503443" target="_blank" >RIV/49777513:23520/10:00503443 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Two-scale modeling of tissue perfusion problem using homogenization of dual porous media

Popis výsledku v původním jazyce

The homogenization approach to the modeling of diffusion in a dual-porous deformable incompressible medium the Biot-type is reported. The model can describe the blood perfusion in biological tissues or uid ltration phenomena in general. Because of the strong heterogeneity in permeability coefcients associated with three compartments of the representative microstructural cell (RMC), the homogenization of the model leads to the double diffusion phenomena. The homogenized model describe the parallel diffusion in two high-conducting compartments (arterial and venous sectors) separated by a low-conducting matrix representing the perfused tissue. To obtain the homogenized model, the method of periodic unfolding is applied. The homogenized coefcients are dened in terms of the characteristic response of the RMC. Viscoelastic and other effective parameters, controlling deformation and the uid redistribution are involved also in time convolutions.

Název v anglickém jazyce

Two-scale modeling of tissue perfusion problem using homogenization of dual porous media

Popis výsledku anglicky

The homogenization approach to the modeling of diffusion in a dual-porous deformable incompressible medium the Biot-type is reported. The model can describe the blood perfusion in biological tissues or uid ltration phenomena in general. Because of the strong heterogeneity in permeability coefcients associated with three compartments of the representative microstructural cell (RMC), the homogenization of the model leads to the double diffusion phenomena. The homogenized model describe the parallel diffusion in two high-conducting compartments (arterial and venous sectors) separated by a low-conducting matrix representing the perfused tissue. To obtain the homogenized model, the method of periodic unfolding is applied. The homogenized coefcients are dened in terms of the characteristic response of the RMC. Viscoelastic and other effective parameters, controlling deformation and the uid redistribution are involved also in time convolutions.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BK - Mechanika tekutin

OECD FORD obor

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Projekt

<a href="/cs/project/GA106%2F09%2F0740" target="_blank" >GA106/09/0740: Mikrostrukturálně orientované hierarchické modelování prokrvení mozku pro vyhodnocení CT perfúzního vyšetření</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal for Multiscale Computational Engineering

ISSN

1543-1649

e-ISSN

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Svazek periodika

8

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

22

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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