TOWARDS MICROSTRUCTURE BASED TISSUE PERFUSION RECONSTRUCTION FROM CT USING MULTISCALE MODELING

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

TOWARDS MICROSTRUCTURE BASED TISSUE PERFUSION RECONSTRUCTION FROM CT USING MULTISCALE MODELING

Popis výsledku v původním jazyce

The paper deals with modeling of blood perfusion and simulation of dynamic CT investigation. The flow can be characterized at several scales for which different models are used. We focus on two levels: flow in larger branching vessels is described usinga simple "1D" model based of the Bernoulli equation. This model is coupled through point sources/sinks with a "0D" model describing multicompartment flows in tissue parenchyma. We propose also a model of homogenized layer which can better reflect arrangement of the microvessels. The research is motivated by modeling liver perfusion which should enable an improved analysis of CT scans. For this purpose we describe a dynamic transport of the contrast fluid at levels of the "1D" and "0D" models, so that time-space distribution of the so-called tissue density can be computed and compared with the measured data obtained form the CT.

Název v anglickém jazyce

TOWARDS MICROSTRUCTURE BASED TISSUE PERFUSION RECONSTRUCTION FROM CT USING MULTISCALE MODELING

Popis výsledku anglicky

The paper deals with modeling of blood perfusion and simulation of dynamic CT investigation. The flow can be characterized at several scales for which different models are used. We focus on two levels: flow in larger branching vessels is described usinga simple "1D" model based of the Bernoulli equation. This model is coupled through point sources/sinks with a "0D" model describing multicompartment flows in tissue parenchyma. We propose also a model of homogenized layer which can better reflect arrangement of the microvessels. The research is motivated by modeling liver perfusion which should enable an improved analysis of CT scans. For this purpose we describe a dynamic transport of the contrast fluid at levels of the "1D" and "0D" models, so that time-space distribution of the so-called tissue density can be computed and compared with the measured data obtained form the CT.

Druh

D - Stať ve sborníku

CEP obor

BK - Mechanika tekutin

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

10th World Congress on Computational Mechanics (WCCM2012)

ISBN

978-85-86686-70-2

ISSN

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e-ISSN

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Počet stran výsledku

18

Strana od-do

1-18

Název nakladatele

Universidade de Sao Paulo

Místo vydání

Sao Paulo

Místo konání akce

Sao Paulo, Brazílie

Datum konání akce

8. 7. 2012

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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