Modeling dynamic CT perfusion test using multicompartment models

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F12%3A43916279" target="_blank" >RIV/49777513:23520/12:43916279 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Modeling dynamic CT perfusion test using multicompartment models

Popis výsledku v původním jazyce

Problem of tissue perfusion reconstruction is quite challenging for the biomechanical and biomedical research. It is desirable to find accurately parts of the tissue with an insufficient blood supply, to localize anomalies in the blood micro-circulationand to quantify locally the perfusion efficiency. To cope with the complexity of the perfusion trees, we use a combination of 3D and 1D fluid dynamics for large and medium vessels, respectively, whereas Darcy flow "0D" models are used to describe blood redistribution in the parenchyma and smaller vessels. In this paper we describe a simplified model on which we test the modeling of the perfusion and tracer transport.The computed perfusion velocities are employed to simulate the dynamic perfusion test. The output of such a simulation can be compared with the clinical CT data scans of the perfusion tests.

Název v anglickém jazyce

Modeling dynamic CT perfusion test using multicompartment models

Popis výsledku anglicky

Problem of tissue perfusion reconstruction is quite challenging for the biomechanical and biomedical research. It is desirable to find accurately parts of the tissue with an insufficient blood supply, to localize anomalies in the blood micro-circulationand to quantify locally the perfusion efficiency. To cope with the complexity of the perfusion trees, we use a combination of 3D and 1D fluid dynamics for large and medium vessels, respectively, whereas Darcy flow "0D" models are used to describe blood redistribution in the parenchyma and smaller vessels. In this paper we describe a simplified model on which we test the modeling of the perfusion and tracer transport.The computed perfusion velocities are employed to simulate the dynamic perfusion test. The output of such a simulation can be compared with the clinical CT data scans of the perfusion tests.

Druh

O - Ostatní výsledky

CEP obor

BK - Mechanika tekutin

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů