Porcine liver vascular bed in Biodur E20 corrosion casts

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23640%2F16%3A43928977" target="_blank" >RIV/49777513:23640/16:43928977 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11140/16:10312637 RIV/49777513:23520/16:43928977 RIV/00669806:_____/16:10312637

Výsledek na webu

<a href="http://dx.doi.org/10.5603/FM.a2015.0094" target="_blank" >http://dx.doi.org/10.5603/FM.a2015.0094</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5603/FM.a2015.0094" target="_blank" >10.5603/FM.a2015.0094</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Porcine liver vascular bed in Biodur E20 corrosion casts

Popis výsledku v původním jazyce

Pigs are frequently used as animal models in experimental medicine. To identify processes of vascular development or regression, vascular elements must be recognised and quantified in a 3D arrangement. Vascular corrosion casts enable the creation of 3D replicas of vascular trees. The aim of our study was to identify suitable casting media and optimise the protocol for porcine liver vascular corrosion casting. Mercox II(R) (Ladd Research, Williston, Vermont, USA) and Biodur E20(R) Plus (Biodur Products, Heidelberg, Germany) were tested in 4 porcine livers. The resins (volume approximately 700 mL) were injected via the portal vein. Corrosion casts were examined by macro-CT, micro-CT and scanning electron microscopy. For hepatectomies, the operating protocol was optimised to avoid gas or blood clot embolisation. Only Biodur E20(R) Plus appeared to be suitable for high-volume vascular corrosion casting due to its optimal permeability, sufficient processing time and minimum fragility. Biodur E20(R) Plus is slightly elastic, radio-opaque and alcohol-resistant. These properties make this acrylic resin suitable for not only vascular research but also teaching purposes.

Název v anglickém jazyce

Porcine liver vascular bed in Biodur E20 corrosion casts

Popis výsledku anglicky

Pigs are frequently used as animal models in experimental medicine. To identify processes of vascular development or regression, vascular elements must be recognised and quantified in a 3D arrangement. Vascular corrosion casts enable the creation of 3D replicas of vascular trees. The aim of our study was to identify suitable casting media and optimise the protocol for porcine liver vascular corrosion casting. Mercox II(R) (Ladd Research, Williston, Vermont, USA) and Biodur E20(R) Plus (Biodur Products, Heidelberg, Germany) were tested in 4 porcine livers. The resins (volume approximately 700 mL) were injected via the portal vein. Corrosion casts were examined by macro-CT, micro-CT and scanning electron microscopy. For hepatectomies, the operating protocol was optimised to avoid gas or blood clot embolisation. Only Biodur E20(R) Plus appeared to be suitable for high-volume vascular corrosion casting due to its optimal permeability, sufficient processing time and minimum fragility. Biodur E20(R) Plus is slightly elastic, radio-opaque and alcohol-resistant. These properties make this acrylic resin suitable for not only vascular research but also teaching purposes.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EA - Morfologické obory a cytologie

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Folia Morphologica

ISSN

0015-5659

e-ISSN

—

Svazek periodika

75

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

8

Strana od-do

154-161

Kód UT WoS článku

000378127700003

EID výsledku v databázi Scopus

2-s2.0-84973402569