Crosslinking Trends in Multicomponent Hydrogels for Biomedical Applications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23640%2F21%3A43963532" target="_blank" >RIV/49777513:23640/21:43963532 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1002/mabi.202100232" target="_blank" >https://doi.org/10.1002/mabi.202100232</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/mabi.202100232" target="_blank" >10.1002/mabi.202100232</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Crosslinking Trends in Multicomponent Hydrogels for Biomedical Applications

Popis výsledku v původním jazyce

Multicomponent-based hydrogels are well established candidates for biomedical applications. However, certain aspects of multicomponent systems, e.g., crosslinking, structural binding, network formation, proteins/drug incorporation, etc., are challenging aspects to modern biomedical research. The types of crosslinking and network formation are crucial for the effective combination of multiple component systems. The creation of a complex system in the overall structure and the crosslinking efficiency of different polymeric chains in an organized fashion are crucially important, especially when the materials are for biomedical applications. Therefore, the engineering of hydrogel has to be, succinctly understood, carefully formulated, and expertly designed. The different crosslinking methods in use, hydrogen bonding, electrostatic interaction, coordination bonding, and self-assembly. The formations of double, triple, and multiple networks, are well established. A systematic study of the crosslinking mechanisms in multicomponent systems, in terms of the crosslinking types, network formation, intramolecular bonds between different structural units, and their potentials for biomedical applications, is lacking and therefore, these aspects require investigations. To this end, the present review, focuses on the recent advances in areas of the physical, chemical, and enzymatic crosslinking methods that are often, employed for the designing of multicomponent hydrogels.

Název v anglickém jazyce

Crosslinking Trends in Multicomponent Hydrogels for Biomedical Applications

Popis výsledku anglicky

Multicomponent-based hydrogels are well established candidates for biomedical applications. However, certain aspects of multicomponent systems, e.g., crosslinking, structural binding, network formation, proteins/drug incorporation, etc., are challenging aspects to modern biomedical research. The types of crosslinking and network formation are crucial for the effective combination of multiple component systems. The creation of a complex system in the overall structure and the crosslinking efficiency of different polymeric chains in an organized fashion are crucially important, especially when the materials are for biomedical applications. Therefore, the engineering of hydrogel has to be, succinctly understood, carefully formulated, and expertly designed. The different crosslinking methods in use, hydrogen bonding, electrostatic interaction, coordination bonding, and self-assembly. The formations of double, triple, and multiple networks, are well established. A systematic study of the crosslinking mechanisms in multicomponent systems, in terms of the crosslinking types, network formation, intramolecular bonds between different structural units, and their potentials for biomedical applications, is lacking and therefore, these aspects require investigations. To this end, the present review, focuses on the recent advances in areas of the physical, chemical, and enzymatic crosslinking methods that are often, employed for the designing of multicomponent hydrogels.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

21001 - Nano-materials (production and properties)

Projekt

<a href="/cs/project/EF17_048%2F0007280" target="_blank" >EF17_048/0007280: Aplikace moderních technologií v medicíně a průmyslu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

MACROMOLECULAR BIOSCIENCE

ISSN

1616-5187

e-ISSN

—

Svazek periodika

21

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

20

Strana od-do

—

Kód UT WoS článku

000708768700001

EID výsledku v databázi Scopus

2-s2.0-85117214723