Clinical outcomes of radiofrequency catheter ablation of atrial fibrillation in octogenarians-10-year experience of a one high-volume center

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12110%2F17%3A43896021" target="_blank" >RIV/60076658:12110/17:43896021 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/17:00098099

Výsledek na webu

<a href="http://dx.doi.org/10.11909/j.issn.1671-5411.2017.09.007" target="_blank" >http://dx.doi.org/10.11909/j.issn.1671-5411.2017.09.007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.11909/j.issn.1671-5411.2017.09.007" target="_blank" >10.11909/j.issn.1671-5411.2017.09.007</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Clinical outcomes of radiofrequency catheter ablation of atrial fibrillation in octogenarians-10-year experience of a one high-volume center

Popis výsledku v původním jazyce

Background Prevalence of atrial fibrillation (AF) increases with age. Radiofrequency catheter ablation (RFCA) is an established treatment option superior to antiarrhythmics (AAs). In this study, we investigated safety and efficacy of RFCA of AF in octogenarians. Methods From our database, we extracted procedural and follow-up data for patients &gt;= 80 years with symptomatic AF undergoing RFCA and compared this population to RFCA patients &lt;= 50 years. All patients underwent pulmonary vein isolation (PVI) supplemented by linear lesions in PVl-nonresponders. Arrhythmia-free survival was assessed using seven day Holter every three months post procedure. All patients completed their 12 months follow-up. Results Fifty patients aged &gt;= 80 years (80.5 +/- 1.6 years) were compared to 259 patients aged &lt;= 50 years (43.5 +/- 5.5 years). The RFCA complication rate did not vary between groups. No differences in procedural characteristics were seen after being analyzed by type of AF. Among patients with paroxysmal AF, 71.4% octogenarian vs. 84.7% young patients was free of any arrhythmia, without AAs, after single procedure. For non-paroxysmal AF, arrhythmia-free survival without AAs, was considerably lower (58.6%) octogenarians vs. 81.2%&gt;younger patients, P = 0.023). If AAs were used, arrhythmia-free survival for paroxysmal AF increased to 90.5%o and 92.1%&gt;in octogenarians and younger patients, respectively; and in non-paroxysmal AF it increased to 79.3%&gt;vs. 88.4%&gt;. Conclusions RFCA is a safe and effective strategy to achieve normal sinus rhythm in a highly selected group of octogenarians. Paroxysmal AF ablation in octogenarians has similar clinical effectiveness as that seen in much younger patients. Non-paroxysmal AF ablation has lower, but still reasonable clinical effectiveness.

Název v anglickém jazyce

Clinical outcomes of radiofrequency catheter ablation of atrial fibrillation in octogenarians-10-year experience of a one high-volume center

Popis výsledku anglicky

Background Prevalence of atrial fibrillation (AF) increases with age. Radiofrequency catheter ablation (RFCA) is an established treatment option superior to antiarrhythmics (AAs). In this study, we investigated safety and efficacy of RFCA of AF in octogenarians. Methods From our database, we extracted procedural and follow-up data for patients &gt;= 80 years with symptomatic AF undergoing RFCA and compared this population to RFCA patients &lt;= 50 years. All patients underwent pulmonary vein isolation (PVI) supplemented by linear lesions in PVl-nonresponders. Arrhythmia-free survival was assessed using seven day Holter every three months post procedure. All patients completed their 12 months follow-up. Results Fifty patients aged &gt;= 80 years (80.5 +/- 1.6 years) were compared to 259 patients aged &lt;= 50 years (43.5 +/- 5.5 years). The RFCA complication rate did not vary between groups. No differences in procedural characteristics were seen after being analyzed by type of AF. Among patients with paroxysmal AF, 71.4% octogenarian vs. 84.7% young patients was free of any arrhythmia, without AAs, after single procedure. For non-paroxysmal AF, arrhythmia-free survival without AAs, was considerably lower (58.6%) octogenarians vs. 81.2%&gt;younger patients, P = 0.023). If AAs were used, arrhythmia-free survival for paroxysmal AF increased to 90.5%o and 92.1%&gt;in octogenarians and younger patients, respectively; and in non-paroxysmal AF it increased to 79.3%&gt;vs. 88.4%&gt;. Conclusions RFCA is a safe and effective strategy to achieve normal sinus rhythm in a highly selected group of octogenarians. Paroxysmal AF ablation in octogenarians has similar clinical effectiveness as that seen in much younger patients. Non-paroxysmal AF ablation has lower, but still reasonable clinical effectiveness.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Geriatric Cardiology

ISSN

1671-5411

e-ISSN

—

Svazek periodika

14

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

CN - Čínská lidová republika

Počet stran výsledku

7

Strana od-do

575-581

Kód UT WoS článku

000418531400006

EID výsledku v databázi Scopus

2-s2.0-85035332806