The Ostrava Region, Czech Republic: impact of air pollution on children´s health

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12110%2F17%3A43896760" target="_blank" >RIV/60076658:12110/17:43896760 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22330/17:43913798

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The Ostrava Region, Czech Republic: impact of air pollution on children´s health

Popis výsledku v původním jazyce

Introduction: The Moravian-Silesian Region (MSR) is heavily polluted, especially due to heavy industry and local heating, and concentrations of benzo[a]pyrene (B[a]P) are among the highest in the European Union. Methods: To verify the impact of air pollution on the health of the population in the MSR, the morbidity of children was analysed in three studies which are reviewed: 1) morbidity in children; 2) asthma bronchiale in children; and 3) impact of air pollution on the genome of newborns. Morbidity in children was studied in 10 pediatric districts in Ostrava City. Asthma bronchiale was studied in children from Ostrava-Radvanice and the control district of Prachatice, southern Bohemia, by gene expression profiles. The impact of air pollution on the genome of newborns was studied in the district of Karvina and the control district of Ceske Budejovice. Results: In asthmatic children from Ostrava, increased gene expression corresponded to the non-allergic type of asthma. Concentrations of benzo[a]pyrene in the winter of 2014 were 5.36 ? 3.64 vs. 1.45 ? 1.19 ng/ m3 in CB, P &lt; 0.001 in Karvina. In newborns in the polluted district of Karvina, increased oxidative damage affecting immunodeficiency pathways and the neurotrophin signalling pathway, higher amounts of OH-metabolites of PAHs in urine, as well as increased respiratory morbidity in children up to two years of age were observed. Conclusion: Studies in the Moravian-Silesian Region indicate a significant impact of air pollution on children?s health

Název v anglickém jazyce

The Ostrava Region, Czech Republic: impact of air pollution on children´s health

Popis výsledku anglicky

Introduction: The Moravian-Silesian Region (MSR) is heavily polluted, especially due to heavy industry and local heating, and concentrations of benzo[a]pyrene (B[a]P) are among the highest in the European Union. Methods: To verify the impact of air pollution on the health of the population in the MSR, the morbidity of children was analysed in three studies which are reviewed: 1) morbidity in children; 2) asthma bronchiale in children; and 3) impact of air pollution on the genome of newborns. Morbidity in children was studied in 10 pediatric districts in Ostrava City. Asthma bronchiale was studied in children from Ostrava-Radvanice and the control district of Prachatice, southern Bohemia, by gene expression profiles. The impact of air pollution on the genome of newborns was studied in the district of Karvina and the control district of Ceske Budejovice. Results: In asthmatic children from Ostrava, increased gene expression corresponded to the non-allergic type of asthma. Concentrations of benzo[a]pyrene in the winter of 2014 were 5.36 ? 3.64 vs. 1.45 ? 1.19 ng/ m3 in CB, P &lt; 0.001 in Karvina. In newborns in the polluted district of Karvina, increased oxidative damage affecting immunodeficiency pathways and the neurotrophin signalling pathway, higher amounts of OH-metabolites of PAHs in urine, as well as increased respiratory morbidity in children up to two years of age were observed. Conclusion: Studies in the Moravian-Silesian Region indicate a significant impact of air pollution on children?s health

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

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OECD FORD obor

30304 - Public and environmental health

Projekt

<a href="/cs/project/GA13-13458S" target="_blank" >GA13-13458S: Dopady znečištění ovzduší na genom novorozenců</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Public Health Panorama

ISSN

2412-544X

e-ISSN

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Svazek periodika

3

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

DK - Dánské království

Počet stran výsledku

9

Strana od-do

156-164

Kód UT WoS článku

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EID výsledku v databázi Scopus

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