Genetic parameters of insect bite hypersensitivity in the Old Grey Kladruber horse

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12220%2F17%3A43896449" target="_blank" >RIV/60076658:12220/17:43896449 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60460709:41210/17:73410 RIV/00027014:_____/17:N0000032

Výsledek na webu

<a href="http://dx.doi.org/10.2527/jas2016.0745" target="_blank" >http://dx.doi.org/10.2527/jas2016.0745</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2527/jas2016.0745" target="_blank" >10.2527/jas2016.0745</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Genetic parameters of insect bite hypersensitivity in the Old Grey Kladruber horse

Popis výsledku v původním jazyce

The objective of this study was to assess the genetic parameters of insect bite hypersensitivity (IBH) in the Old Grey Kladruber horse, an original Czech warmblood horse breed. Insect bite hypersensitivity is a recurrent allergic skin disease affecting horses worldwide. Its etiology is multifactorial. The defect is genetically controlled, and the starting impulse is a bite by midges of the Culicoides spp. and less frequently Simulium spp. Knowledge about the associated genes is limited. Horses were kept by the National Stud in Kladruby (1,146 measurements) and by 10 private breeders (63 measurements). The horses were visually scored by the same inspector over a period of 13 yr from 1996 to 2009. A linear logistic model with a binary variable was used for subsequent statistical analysis. The fixed effects of the farm, year of evaluation, age of evaluation, and sex were significant, and the nonsignificant effect was the intensity of greying. The animals from the National Stud were more strongly affected by IBH than animals from private studs. The National Stud is located near the Labe River, at an altitude of 206 m; there are bottomland pastures in the vicinity, blind river arms, and numerous pools and marshes, and the climate is mild. These conditions are convenient for horse keeping but also for the propagation of Culicoides. The stallions were less affected than the mares. The occurrence in years of age was influenced by selection; scoring began in the first year of age, and when the young animal was repeatedly positive, it was eliminated from breeding. The estimated h2 differed significantly from 0, and the direct h2 were 0.626 in the animal model with a maternal effect, 0.359 in the animal model without a maternal effect, and 0.363 in the animal model without correlation between direct and maternal effect. The maternal h2 was 0.305. The estimated repeatabilities were 0.636 with a maternal effect, 0.615 without a maternal effect, and 0.623 without correlation. The h2 of IBH was found to be medium to high, so there is a possibility to reduce the prevalence of IBH by selection.

Název v anglickém jazyce

Genetic parameters of insect bite hypersensitivity in the Old Grey Kladruber horse

Popis výsledku anglicky

The objective of this study was to assess the genetic parameters of insect bite hypersensitivity (IBH) in the Old Grey Kladruber horse, an original Czech warmblood horse breed. Insect bite hypersensitivity is a recurrent allergic skin disease affecting horses worldwide. Its etiology is multifactorial. The defect is genetically controlled, and the starting impulse is a bite by midges of the Culicoides spp. and less frequently Simulium spp. Knowledge about the associated genes is limited. Horses were kept by the National Stud in Kladruby (1,146 measurements) and by 10 private breeders (63 measurements). The horses were visually scored by the same inspector over a period of 13 yr from 1996 to 2009. A linear logistic model with a binary variable was used for subsequent statistical analysis. The fixed effects of the farm, year of evaluation, age of evaluation, and sex were significant, and the nonsignificant effect was the intensity of greying. The animals from the National Stud were more strongly affected by IBH than animals from private studs. The National Stud is located near the Labe River, at an altitude of 206 m; there are bottomland pastures in the vicinity, blind river arms, and numerous pools and marshes, and the climate is mild. These conditions are convenient for horse keeping but also for the propagation of Culicoides. The stallions were less affected than the mares. The occurrence in years of age was influenced by selection; scoring began in the first year of age, and when the young animal was repeatedly positive, it was eliminated from breeding. The estimated h2 differed significantly from 0, and the direct h2 were 0.626 in the animal model with a maternal effect, 0.359 in the animal model without a maternal effect, and 0.363 in the animal model without correlation between direct and maternal effect. The maternal h2 was 0.305. The estimated repeatabilities were 0.636 with a maternal effect, 0.615 without a maternal effect, and 0.623 without correlation. The h2 of IBH was found to be medium to high, so there is a possibility to reduce the prevalence of IBH by selection.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40101 - Agriculture

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Animal Science

ISSN

0021-8812

e-ISSN

—

Svazek periodika

1

Číslo periodika v rámci svazku

95

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

53-58

Kód UT WoS článku

000397115100006

EID výsledku v databázi Scopus

—