The phylogenetic analysis of a novel genetic subtype of caprine arthritis encephalitis virus (CAEV) in the Czech Republic

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12220%2F19%3A43899528" target="_blank" >RIV/60076658:12220/19:43899528 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=6168&category_id=150&option=com_virtuemart&vmcchk=1&Itemid=1" target="_blank" >http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=6168&category_id=150&option=com_virtuemart&vmcchk=1&Itemid=1</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4149/av_2019_215" target="_blank" >10.4149/av_2019_215</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The phylogenetic analysis of a novel genetic subtype of caprine arthritis encephalitis virus (CAEV) in the Czech Republic

Popis výsledku v původním jazyce

Lentiviruses of sheep and goats, referred to as small ruminant lentiviruses (SRLV) cause severe diseases that affect health, productivity and international animal trade causing significant economical losses. Infections with Maedi visna virus (MAEV) and caprine arthritis-encephalitis virus (CAEV) are characterized with long incubation period and sheep and goats persist infected for life. Both infections are subclinical and viruses can be spread and propagated without any clinical symptoms for months or years and can lead to death of infected animals. In this study we analyse genotypes of small ruminant lentiviruses in an imported goat herd from France using the molecular approach. 35 animals from one goat flock were analysed. Based on the analysis of the TMEM154 gene, all goats belong to the E35 haplotype group with a higher risk of SRLV infection. This is the first finding of B1 genotype of SRLV in the small ruminant flocks in the Czech Republic. Since there is often a cross infection of lentivirus genotypes between sheep and goats, it can be assumed that a new strain will be spread among flocks of small ruminants in the future in the Czech Republic.

Název v anglickém jazyce

The phylogenetic analysis of a novel genetic subtype of caprine arthritis encephalitis virus (CAEV) in the Czech Republic

Popis výsledku anglicky

Lentiviruses of sheep and goats, referred to as small ruminant lentiviruses (SRLV) cause severe diseases that affect health, productivity and international animal trade causing significant economical losses. Infections with Maedi visna virus (MAEV) and caprine arthritis-encephalitis virus (CAEV) are characterized with long incubation period and sheep and goats persist infected for life. Both infections are subclinical and viruses can be spread and propagated without any clinical symptoms for months or years and can lead to death of infected animals. In this study we analyse genotypes of small ruminant lentiviruses in an imported goat herd from France using the molecular approach. 35 animals from one goat flock were analysed. Based on the analysis of the TMEM154 gene, all goats belong to the E35 haplotype group with a higher risk of SRLV infection. This is the first finding of B1 genotype of SRLV in the small ruminant flocks in the Czech Republic. Since there is often a cross infection of lentivirus genotypes between sheep and goats, it can be assumed that a new strain will be spread among flocks of small ruminants in the future in the Czech Republic.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

40301 - Veterinary science

Projekt

<a href="/cs/project/QJ1610096" target="_blank" >QJ1610096: Program zdravotní kontroly lentivirových infekcí malých přežvýkavců s využitím nových metod časné laboratorní diagnostiky a markerů geneticky podmíněné rezistence k infekci jako selekčního kritéria</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Virologica

ISSN

0001-723X

e-ISSN

—

Svazek periodika

63

Číslo periodika v rámci svazku

13

Stát vydavatele periodika

SK - Slovenská republika

Počet stran výsledku

3

Strana od-do

240-242

Kód UT WoS článku

000485186100015

EID výsledku v databázi Scopus

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