Somatic cell score: gene polymorphisms and other effects in Holstein and Simmental cows

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12220%2F22%3A43902907" target="_blank" >RIV/60076658:12220/22:43902907 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/26722861:_____/22:N0000002 RIV/00027014:_____/22:N0000004

Výsledek na webu

<a href="https://www.animbiosci.org/journal/view.php?doi=10.5713/ab.20.0720" target="_blank" >https://www.animbiosci.org/journal/view.php?doi=10.5713/ab.20.0720</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5713/ab.20.0720" target="_blank" >10.5713/ab.20.0720</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Somatic cell score: gene polymorphisms and other effects in Holstein and Simmental cows

Popis výsledku v původním jazyce

The aim of the study was to evaluate the influence of gene polymorphisms and nongenetic factors on the somatic cell score (SCS) in the milk of Holstein (n = 148) and Simmental (n = 73) cows and their crosses (n = 6). The SCS was calculated by the formula SCS = log2(SCC/100,000)+3, where SCC is the somatic cell count. Polymorphisms in the casein alpha S1 (CSN1S1), beta-casein (CSN2), kappa-casein (CSN3), beta-lactoglobulin (LGB), acyl-CoA diacylglycerol transferase 1 (DGAT1), leptin (LEP), fatty acid synthase (FASN), stearoyl CoA desaturase 1 (SCD1), and 1-acylglycerol-3-phosphate O-acyltransferase 6 (AGPAT6) genes were genotyped, and association analysis to the SCS in the cow&apos;s milk was performed. Further, the impact of breed, farm, year, month of the year, lactation stage and parity on the SCS were analysed. Phenotype correlations among SCS and milk constituents were computed by Pearson correlation coefficients. Only CSN2 genotypes A(1)/A(2) were found to have significant association with the SCS (p&lt;0.05), and alleles of CSN1S1 and DGAT1 genes (p&lt;0.05). Other polymorphisms were not found to be significant. SCS had significant association with the combined effect of farm and year, lactation stage and month of the year. Lactation parity and breed had not significant association with SCS. The phenotypic correlation of SCS to lactose content was negative and significant, while the correlation to protein content was positive and significant. The correlations of SCS to fat, casein, nonfat solids, urea, citric acid, acetone and ketones contents were very low and not significant. Only CSN2 genotypes, CSN1S1 and DGAT1 alleles did show an obvious association to the SCS. The results confirmed the importance of general quality management of farms on the microbial milk quality, and effects of lactation stage and month of the year. The lactose content in milk reflects the health status of the udder.

Název v anglickém jazyce

Somatic cell score: gene polymorphisms and other effects in Holstein and Simmental cows

Popis výsledku anglicky

The aim of the study was to evaluate the influence of gene polymorphisms and nongenetic factors on the somatic cell score (SCS) in the milk of Holstein (n = 148) and Simmental (n = 73) cows and their crosses (n = 6). The SCS was calculated by the formula SCS = log2(SCC/100,000)+3, where SCC is the somatic cell count. Polymorphisms in the casein alpha S1 (CSN1S1), beta-casein (CSN2), kappa-casein (CSN3), beta-lactoglobulin (LGB), acyl-CoA diacylglycerol transferase 1 (DGAT1), leptin (LEP), fatty acid synthase (FASN), stearoyl CoA desaturase 1 (SCD1), and 1-acylglycerol-3-phosphate O-acyltransferase 6 (AGPAT6) genes were genotyped, and association analysis to the SCS in the cow&apos;s milk was performed. Further, the impact of breed, farm, year, month of the year, lactation stage and parity on the SCS were analysed. Phenotype correlations among SCS and milk constituents were computed by Pearson correlation coefficients. Only CSN2 genotypes A(1)/A(2) were found to have significant association with the SCS (p&lt;0.05), and alleles of CSN1S1 and DGAT1 genes (p&lt;0.05). Other polymorphisms were not found to be significant. SCS had significant association with the combined effect of farm and year, lactation stage and month of the year. Lactation parity and breed had not significant association with SCS. The phenotypic correlation of SCS to lactose content was negative and significant, while the correlation to protein content was positive and significant. The correlations of SCS to fat, casein, nonfat solids, urea, citric acid, acetone and ketones contents were very low and not significant. Only CSN2 genotypes, CSN1S1 and DGAT1 alleles did show an obvious association to the SCS. The results confirmed the importance of general quality management of farms on the microbial milk quality, and effects of lactation stage and month of the year. The lactose content in milk reflects the health status of the udder.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

40201 - Animal and dairy science; (Animal biotechnology to be 4.4)

Projekt

<a href="/cs/project/QJ1510336" target="_blank" >QJ1510336: Výzkum a podpora produkce zdravotně a spotřebitelsky benefitních mléčných výrobků cílenou selekcí a modifikací profilu mastných kyselin mléčného tuku</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Animal Bioscience

ISSN

2765-0189

e-ISSN

2765-0235

Svazek periodika

35

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

KR - Korejská republika

Počet stran výsledku

9

Strana od-do

13-21

Kód UT WoS článku

000737054900002

EID výsledku v databázi Scopus

2-s2.0-85122990012